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Table 2 Multivariable analysis of women who experience their first miscarriage versus live birth*

From: Prevalence and clinical, social, and health care predictors of miscarriage

Variable Model 1: RD (95%CI) n = 79,978 Model 2: RD (95%CI) n = 79,846 Model 3: RD (95%CI) n = 79,846
Year of event −0.0002 (− 0.001, 0.001) −0.0001 (0.001, 0.001) − 0.000 (− 0.001, 0.001)
Clinical
 Paritya
  Primiparous vs. nulliparous −0.03 (− 0.04, − 0.02) −0.03 (− 0.03, − 0.02) −0.02 (− 0.03, − 0.02)
  Multiparous vs. nulliparous −0.03 (− 0.03, − 0.02) −0.03 (− 0.03, − 0.02) −0.02 (− 0.03, − 0.02)
 Previous c-sectiona 0.01 (0.001, 0.016) 0.01 (0.001, 0.02) 0.01 (− 0.002, 0.01)
 Diabetesb 0.02 (0.01, 0.03) 0.02 (0.002, 0.03) 0.004 (−0.01, 0.02)
 Endometriosisb 0.03 (−0.002, 0.07) 0.03 (0.0002, 0.07) 0.02 (−0.01 0.06)
 Hypertensionc −0.01 (− 0.02, 0.01) −0.01 (− 0.02, 0.008) −0.02 (− 0.03, − 0.004)
 Infertility drug used 0.04 (0.02, 0.06) 0.04 (0.03, 0.06) 0.04 (0.02, 0.06)
 Mood or anxiety disordersd 0.04 (0.03, 0.05) 0.04 (0.03, 0.05) 0.02 (0.02, 0.03)
 Substance abused 0.004 (−0.01, 0.02) 0.002 (−0.01, 0.02) − 0.01 (− 0.03, 0.01)
 Suicide attempte 0.05 (0.02, 0.08) 0.04 (0.01, 0.07) 0.03 (−0.002, 0.07)
Social f, g
 Mother’s SEFIh   0.01 (0.004, 0.01) 0.01 (0.005, 0.01)
 Income assistancei   −0.02 (−0.03, − 0.02) −0.03 (− 0.04, − 0.02)
Health care use
 Morbidity (RUB)c
  0 vs. 2    −0.03 (− 0.04, − 0.03)
  1 vs. 2    0.03 (0.02, 0.03)
  3 vs. 2    0.04 (0.03, 0.04)
  4+ vs. 2    0.12 (0.09, 0.15)
 Hospitalization costs (2010$)c, j    0.004 (0.003, 0.006)
 Amb. phys. Costs (2010$)c, j    0.01 (−0.02, 0.03)
 Psychotropic Rx costs (2010$)k, l    −0.002 (− 0.004, 0.0002)
  1. RD risk difference, CI confidence interval, RUB Resource Utilization Band, SEFI Socioeconomic Factor Index, Amb. phys Ambulatory family physician, Rx prescription, LOS Length of stay
  2. *All models control for maternal age; models 2 and 3 additionally control for regional of residence (refer to Additional file 5 for coefficients). Model 1: Miscarriage as a function of year, maternal age, and clinical covariates; Model 2: Miscarriage as a function of year, maternal age, and clinical+social covariates; Model 3: Miscarriage as a function of year, maternal age, and clinical+social+healthcare use covariates. All models use the binomial distribution and an identity link to obtain RDs
  3. aSince 1984; bIn the 3 years before event; cIn the year before event; dIn the 2 years before event; eIn the 5 years before event; fReference age = 29; gReference region: Central; hAt time of event; iFor at least one month in the year before event; jIn $1000 increments; kOver a 1-year period starting 2 years before the event date, lIn $100 increments