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Table 2 Maternal Frailty (MaFra) Inventory. Intrauterine and extrauterine preterm birth risk factors included in the MaFra Inventory. 150 items assess the 71 listed factors while 24 Items collect more general sociodemographic, anamnestic and basic pregnancy history information for a total of 174 items included in the MaFra Inventory

From: A hierarchical procedure to select intrauterine and extrauterine factors for methodological validation of preterm birth risk estimation

System Pregnancy anamnesis Factors Number of items High/ low risk Uterine environment Study
UTERINE PREVIOUS (Conditions of Pregnancy) Parity 1 L U [34]
UTERINE PREVIOUS (Conditions of Pregnancy) Delivery Onset 2 L U [35]
UTERINE PREVIOUS (Conditions of Pregnancy) Breastfeeding 1 L U [36]
UTERINE PREVIOUS (Conditions of Pregnancy) Multiple Gestation 1 L U [37]
UTERINE PREVIOUS (Conditions of Pregnancy) Voluntary Interruption of Pregnancy 1 L U [38]
UTERINE PREVIOUS (Conditions of Pregnancy) Miscarriage 1 L U [38]
UTERINE PREVIOUS (Conditions of Pregnancy) Prior PTB 2 H U [4]
UTERINE CURRENT (Conditions of Pregnancy) Fetal Growth Restriction 9 H F [9]
UTERINE CURRENT (Conditions of Pregnancy) Medically Assisted Procreation 2 H U [22]
UTERINE CURRENT (Conditions of Pregnancy) Short Cervical Length 1 H U [19]
UTERINE CURRENT (Conditions of Pregnancy) Placenta Previa 1 H P [24]
UTERINE CURRENT (Conditions of Pregnancy) Placental Abruption 1 H P [5]
UTERINE CURRENT (Conditions of Pregnancy) Uterine Fibroid (Leiomyomas) 1 L U [39]
UTERINE CURRENT (Conditions of Pregnancy) Polidramnios 1 H U [20]
UTERINE CURRENT (Conditions of Pregnancy) Oligoidramnios 1 L U [40]
UTERINE CURRENT (Conditions of Pregnancy) Fetal Fibronectin 1 H F [41]
UTERINE CURRENT (Conditions of Pregnancy) Interleukin (IL)-6-Inflammatory Cytokine 1 H U [42]
UTERINE CURRENT (Conditions of Pregnancy) Fetal Sex 1 L F [43]
UTERINE CURRENT (Conditions of Pregnancy) Pregnancy Induced Hypertension (PIH) 1 H P [44]
UTERINE CURRENT (Conditions of Pregnancy) Preeclampsia 3 H P [45]
EXTRAUTERINE CURRENT (Conditions of Pregnancy) Pregnancy Awareness 10 L - [46]
EXTRAUTERINE CURRENT (Conditions of Pregnancy) Obesity 4 L - [47]
EXTRAUTERINE CURRENT (Conditions of Pregnancy) Gestational Diabetes 2 L - [48]
EXTRAUTERINE CURRENT (Conditions of Pregnancy) Thyroid Disease 2 L - [49]
EXTRAUTERINE CURRENT (Conditions of Pregnancy) Autoimmune Syndrome 1 H - [27]
EXTRAUTERINE CURRENT (Conditions of Pregnancy) Urinary Tract Infection (UTI) 1 H - [26]
EXTRAUTERINE CURRENT (Conditions of Pregnancy) Fever 1 L - [50]
EXTRAUTERINE CURRENT (Conditions of Pregnancy) Rubella 1 L - [51]
EXTRAUTERINE CURRENT (Conditions of Pregnancy) Infection 4 L - [52]