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Table 2 Sleep disturbancies, physical and mental QoL and associations with NVP. Total n = 1203

From: Sleep quality in women with nausea and vomiting of pregnancy: a cross-sectional study

 

All

  

No NVP

Mild NVP

Moderate NVP

Severe NVP

    

PUQE 3 points

PUQE 4–6 points

PUQE 7–12 points

PUQE ≥ 13 points

 

n = 1203

  

n = 136

n = 361

n = 629

n = 77

 

n (%)

pa

pb

n (%)

OR

n (%)

OR

95% CI

AORa

95% CI

n (%)

OR

95% CI

AORa

95% CI

n (%)

OR

95% CI

AORa

95% CI

Difficulty falling asleep

 

0.005

0.026

 

1

 

1.05

0.37–2.98

1.00

0.30–3.18

 

2.66

1.04–6.75

2.46

0.86–7.07

 

3.01

0.95–9.57

3.00

0.80–11.29

 Yes (≥ 3 times a week)

85 (7.1)

  

5 (0.4)

 

14 (1.1c)

    

58 (4.8)

    

8 (0.7)

    

 No (≤ 1–2 times a week)

1113 (92.9)

  

130 (10.9)

 

346 (28.9)

    

568 (47.4)

    

69 (5.8)

    

Night awakenings

 

< 0.0001

< 0.0001

 

1

 

1.34

0.90–2.01

1.33

0.86–2.05

 

2.39

1.62–3.52

2.08

1.38–3.15

 

3.87

1.95–7.70

3.90

1.79–8.47

 Yes (≥ 3 times a week)

837 (69.9)

  

75 (6.3)

 

227 (19.0)

    

471 (39.4)

    

64 (5.4)

    

 No (≤ 1–2 times a week)

360 (30.1)

  

59 (4.9)

 

133 (11.1)

    

155 (12.9b)

    

13 (1.0b)

    

Too early morning awakenings

 

0.0008

0.013

 

1

 

2.02

0.82–4.95

1.81

0.72–4.53

 

3.82

1.64–8.91

3.16

1.33–7.49

 

3.97

1.42–11.04

3.05

0.99–9.37

 Yes (≥ 3 times a week)

143 (12.0)

  

6 (0.5)

 

31 (2.6)

    

94 (7.9)

    

12 (1.00)

    

 No (≤ 1–2 times a week)

1053 (88.0)

  

129 (10.8)

 

330 (27.6)

    

529 (44.2)

    

65 (5.4)

    

Sleepiness during the day

 

< 0.0001

< 0.0001

 

1

 

2.87

1.67–4.95

2.90

1.60–5.28

 

4.93

2.93–8.29

5.07

2.86–8.97

 

4.15

2.11–8.15

4.67

2.20–9.94

 Yes (≥ 3 times a week)

427 (35.7)

  

18 (1.5)

 

110 (9.2)

    

269 (22.5)

    

30 (2.5)

    

 No (≤ 1–2 times a week)

768 (64.3)

  

117 (9.8)

 

249 (20.9b)

    

355 (29.7)

    

47 (3.9)

    
 

Mean ± SD

  

Mean ± SD

 

Mean ± SD

    

Mean ± SD

    

Mean ± SD

    

General sleep quality VAS

53.5 ± 30.5

< 0.0001

< 0.0001

3.6 ± 9.1

1

40.7 ± 25.0

1.05

1.03–1.06

1.05

1.03–1.07

67.3 ± 21.7

1.07

1.05–1.09

1.07

1.06–1.09

81.6 ± 18.5

1.08

1.06–1.10

1.09

1.07–1.11

Physical QoL VAS

33.7 ± 28.4

< 0.0001

< 0.0001

3.6 ± 10.4

1

23.7 ± 21.7

1.17

1.13–1.20

1.20

1.16–1.25

43.0 ± 27.2

1.22

1.18–1.26

1.25

1.20–1.31

55.4 ± 30.2

1.28

1.23–1.32

1.32

1.26–1.39

Mental QoL VAS

31.4 ± 25.6

< 0.0001

< 0.0001

10.9 ± 17.5

1

25.0 ± 23.2

1.12

1.09–1.15

1.14

1.10–1.17

37.5 ± 25.0

1.15

1.12–1.19

1.17

1.13–1.21

45.5 ± 26.1

1.17

1.14–1.21

1.19

1.15–1.23

  1. Odds ratios presented with 95% confidence interval
  2. AOR Adjusted odds ratio, BMI Body mass index, NVP Nausea and vomiting of pregnancy, PUQE Pregnancy-Unique Quantification of Emesis questionnaire, Sleep disturbances were assessed with Basic Nordic Sleep Questionnaire, QoL Quality of life, VAS Visual analog scale
  3. aUnivariate analysis (multinomial logistic regression analysis)
  4. bAdjusted for age, parity, BMI, smoking and employment (multinomial logistic regression analysis)
  5. cResults rounded up with one decimal