Table 2 Follow-up on fetus with combined ARSA and chromosomal abnormalities
Numerical order | Age cohorts | Pregnant week | Additional anomalies (intracardiac or extracardiac) | Serum screening result | Cell-free DNA | Karyotype | Outcome |
|---|---|---|---|---|---|---|---|
NO.1 | AMA | 32 | perimembranous ventricular septal defect; single umbilical artery; pyelectasis | positive | high risk | 21-T | terminated |
NO.2 | AMA | 26 | unilateral cleft lip with alveolar cleft; single renal cyst | negative | high risk | 21-T | terminated |
NO.3 | AMA | 23 | tetralogy of Fallot; | negative | high risk | 21-T | terminated |
NO.4 | AMA | 22 | strawberry head; unilateral strephenopodia; fingers flexion and overlap; left ventricular dysplasia | positive | high risk | 18-T | terminated |
NO.5 | non-AMA | 23 | mild lateral ventricular dilatation; slight tricuspid regurgitation; eyes spacing widened | positive | high risk | 21-T | terminated |
NO.6 | non-AMA | 32 | omphalocele; angle of iliac ala increases | negative | high risk | 21-T | terminated |
NO.7 | non-AMA | 12 | increased nuchal translucency; hypoplastic nasal bone | positive | high risk | 21-T | terminated |
NO.8 | non-AMA | 26 | • persistent left superior vena cava; coronary sinus dilatation | positive | high risk | 21-T | terminated |
NO.9 | non-AMA | 24 | perimembranous ventricular septal defect; micromandible; low-set ears; unilateral complete cleft palate (III) | positive | high risk | 18-T | terminated |
NO.10 | non-AMA | 28 | increased nuchal fold; Dandy-Walker malformation; double outlet right ventricle | positive | high risk | 18-T | terminated |
NO.11 | non-AMA | 33 | left ventricular hyperechoic plaques; polycystic renal dysplasia; semilobarholoprosencephaly; cyclopia; beak nose; intrauterine growth restriction | negative | high risk | 13-T | terminated |