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Table 2 Comparison of baseline characteristics among women divided according to vaginal flora in early stage of pregnancy

From: Relationship between vaginal group B streptococcus colonization in the early stage of pregnancy and preterm birth: a retrospective cohort study

 

GBS in early stage of pregnancy

Positive

n = 61

Negative

n = 1018

p-value

GA at examination, weeks, median [range]

14.3 [13.6–16.3]

14.4 [11.3–17.7]

0.863

Maternal age, years old

34.8 ± 4.6

34.2 ± 4.9

0.277

Nullipara

 Yes

43 (70.5)

594 (58.3)

0.042*

 No

18 (29.5)

424 (41.7)

 

Overweight (BMI ≥ 25)

 Yes

6 (9.8)

99 (9.7)

0.977

 No

55 (90.2)

919 (90.3)

 

Diabetes mellitus

 Yes

3 (4.9)

27 (2.7)

0.417

 No

58 (95.1)

991 (97.3)

 

Thyroid disease

 Yes

2 (3.3)

71 (7.0)

0.427

 No

59 (96.7)

947 (93.0)

 

GDM

 Yes

5 (8.2)

123 (12.1)

0.373

 No

56 (91.8)

895 (87.9)

 

Preterm PROM

 Yes

2 (3.3)

19 (1.9)

0.335

 No

59 (96.7)

999 (98.1)

 

Term PROM

 Yes

14 (23.0)

146 (14.3)

0.062

 No

47 (77.0)

872 (85.7)

 

GA at delivery, weeks, median [range]

39.4 [29.9–42.0]

39.4 [32.3–42.7]

0.938

Preterm birth < 34 weeks

 Yes

4 (6.6)

5 (0.5)

0.001*

 No

57 (93.4)

1013 (99.5)

 

Preterm birth < 37 weeks

 Yes

6 (9.8)

44 (4.3)

0.047*

 No

55 (90.2)

974 (95.7)

 

Sex

 Male

32 (52.5)

533 (52.4)

0.988

 Female

29 (47.5)

485 (47.6)

 

Birth weight, kg, median [range]

3.0 [1.4–4.4]

3.1 [1.5–4.3]

0.433

Apgar score at 1 min

 Low Apgar score (<  7 points)

6 (9.8)

53 (5.2)

0.122

 ≥ 7 points

55 (90.2)

965 (94.8)

 

Apgar score at 5 min

 Low Apgar score (<  7 points)

3 (4.9)

13 (1.3)

0.057

 ≥ 7 points

58 (95.1)

1005 (98.7)

 

NICU admission

 Yes

10 (16.4)

109 (10.7)

0.168

 No

51 (83.6)

909 (89.3)

 

Neonatal GBS disease

 Yes

0 (0.0)

0 (0.0)

 No

61 (100)

1018 (100)

 
  1. Data are presented as means ± standard deviation or median [range] for continuous variables and n (%) for categorical variables
  2. GBS Group B Streptococcus, GA Gestational age, BMI Body mass index, GDM Gestational diabetes mellitus, PROM Premature rupture of membranes, NICU Neonatal Intensive Care Unit
  3. *Statistically significant