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Table 4 Logistic regression model of the association of maternal circulating vitamin B12 deficiency markers with probable postpartum depression based on Edinburg Postpartum Depression Scale (EPDS) cut-off of > 10

From: Cross-sectional association between vitamin B12 status and probable postpartum depression in Indian women

Model Vitamin B12 metabolites Odds ratio 95% CI p-value Predictive value of the model
Unadjusted Total B12 0.355 0.175–0.718 0.004 76.5%
MMA 1.99 1.53–2.59 < 0.001
5-methyl THF 2.96 1.46–6.01 0.003
Hcy 1.45 1.00–2.09 0.048
holotc 0.979 0.641–1.497 0.922
SAM 0.74 0.573–0.967 0.027
Serotonin 0.844 0.581–1.22 0.372
cB12 0.357 0.239–0.532 < 0.0001
Adjusteda Total B12 0.514 0.289–0.912 0.009 78.6%
MMA 2.04 1.53–2.11 < 0.001
5-methyl THF 3.18 1.42–6.08 0.001
Hcy 1.42 0.959–2.1 0.079
holotc 0.968 0.61–1.49 0.893
SAM 0.762 0.59–1.01 0.063
Serotonin 0.832 0.573–1.21 0.309
cB12 0.312 0.192–0.501 < 0.001
  1. aAdjusted for socioeconomic status, marital dissatisfaction, unplanned pregnancy and type of delivery