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Table 4 Comparison of single and double blastocyst embryo transfer cycle results between January 2014 – July 2019 in women between 35 and 42 years of age with a history of either no previous attempts or 1, 2 or 3 attempts

From: Incidence of multiple births in relation to current regulations in Turkey regarding embryo transfer

 

SBT

n = 1114

DBT

n = 473

P-value

Age years, mean ± SD

37.32 ± 2.02

37.60 ± 2.11

a < 0.05*

AMH, (ng/ml), mean ± SD

2.16 ± 2.28

1.93 ± 2.14

a0.09

BMI, (kg/m2), mean ± SD

25.07 ± 4.79

25.38 ± 4.70

a0.236

Number of aspirated oocytes, mean ± SD

10.89 ± 8.29

10.14 ± 7.27

a0.074

MII, mean ± SD

9.19 ± 6.92

8.31 ± 5.66

a < 0.01*

PN2, mean ± SD

7.59 ± 5.85

6.98 ± 4.77

a < 0.05*

Implantation Rate, (%)

59.6

36.2

a < 0.001*

Biochemical Pregnancy, n (%)

718 (64.4)

291 (61.5)

b0.25

Clinical Pregnancy, n (%)

659 (59.1)

256 (54.1)

b0.055

Biochemical losses, n (%)

59 (8.2)

35 (12)

b0.045*

Clinical Miscarriage n (%)

76 (11.5)

56 (21.9)

b < 0.001*

Total Live Birth, n (%)

569 (51)

194 (41)

b < 0.001*

 Singleton Live Birth, n (%)

559 (98.2)

138 (71.1)

b < 0.001*

 Twin Live Birth, n (%)

10 (1.8)

55 (28.4)

b < 0.001*

 Triplet Live Birth, n (%)

1 (0.4)

N/A

Term Live Birth, n (%)

491 (86.3)

129 (66.5)

b < 0.001*

Preterm Live Birth, n (%)

78 (13.7)

65 (33.5)

b < 0.001*

  1. SET Single blastocyst transfer, DET Double blastocyst transfer, AMH Anti-Mullerian Hormone, BMI Body mass index
  2. aIndependent Two Samples t-Test bChi-Squared Test *p < 0,05