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Table 4 Multivariable analyses of factors associated with clinically significant weight loss and neonatal hyperbilirubinemia

From: Outcomes for 298 breastfed neonates whose mothers received ketamine and diazepam for postpartum tubal ligation in a resource-limited setting

Variable

Clinically significant weight loss N = 291

Neonatal hyperbilirubinemia N = 287

Adjusted OR (95% CI)

p value

Adjusted OR (95% CI)

p value

Ketamine dose (mg/kg)a

0.77 (0.31–1.92)

0.581

0.86 (0.38–1.94)

0.719

IV diazepam dose (mg/10 kg)a

1.95 (1.13–3.34)

0.016

1.87 (1.11–3.13)

0.017

PO diazepam

No

Reference group

–

Reference group

–

Yes

0.70 (0.24–1.98)

0.497

1.11 (0.38–2.52)

0.803

Karen Ethnicity

No

–

–

Reference group

–

Yes

–

–

0.80 (0.37–1.72)

0.561

Pre-eclampsia

No

–

–

Reference group

 

Yes

–

–

0.72 (0.19–2.65)

0.620

Maternal obesity (BMI ≥ 27.5 kg/m2)

No

–

–

Reference group

–

Yes

–

–

3.71 (1.40–9.83)

0.008

Maternal Underweight (BMI < 18.5 kg/m2)

No

Reference group

–

–

–

Yes

3.97 (1.18–13.37)

0.026

–

–

Postpartum hemorrhage > 1 L

No

Reference group

–

–

–

Yes

4.38 (0.46–42.14)

0.200

–

–

5 Minute Apgar Score

9 or 10

Reference group

–

–

–

≤8

6.53 (0.23–186.07)

0.272

–

–

Infant sex

Male

–

–

Reference group

–

Female

–

–

1.11 (0.51–2.44)

0.782

EGA at birth

≥ 39 wks

Reference group

–

Reference group

–

37- < 39 wks

0.75 (0.23–2.43)

0.634

2.15 (0.96–4.84)

0.064

  1. Abbreviations: EGA estimated gestational age, BMI body mass index, L liter, IV intravenous, PO per oral
  2. amedian [range]