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Table 2 Univariate analysis of factors associated with clinically significant weight loss (CSWL) ≥ 95th percentile

From: Outcomes for 298 breastfed neonates whose mothers received ketamine and diazepam for postpartum tubal ligation in a resource-limited setting

Continuous Variables

No CSWL

CSWL

Crude OR (95% CI)

p value

 Ketamine dose (mg/kg)a N = 293

1.16 [0.46–3.80]

1.14 [0–2.27]

0.92 (0.34–2.49)

0.869

 IV diazepam dose (mg/10 kg)a N = 293

1.47 [0–4.35]

1.82 [0.96–6.15]

1.94 (1.20–3.16)

0.007

 Lidocaine dose (mg)a N = 290

100 [50–200]

100 [100–150]

1.00 (0.98–1.02)

0.801

Categorical Variables

 

Percent (n) CSWL

Crude OR (95% CI)

p value

 PO diazepam N = 297

No

8.0 (12/150)

Reference group

 

Yes

4.8 (7/147)

0.58 (0.22–1.50)

0.259

 Maternal age (years) N = 298

≤33

6.6 (10/152)

Reference group

 

> 33

6.2 (9/146)

0.93 (0.37–2.37)

0.884

 Parity N = 298

≤ 2

7.5 (5/67)

Reference group

 

> 2

6.1 (14/231)

0.80 (0.28–2.31)

0.680

 BMI N = 298

≥ 18.5

5.2 (14/271)

Reference group

 

< 18.5

18.5 (5/27)

4.17 (1.37–12.66)

0.012

 Postpartum hemorrhage > 1 L N = 298

No

6.2 (18/291)

Reference group

 

Yes

14.3 (1/7)

2.53 (0.29–22.14)

0.402

 5 Minute Apgar Score N = 296

9 or 10

6.1 (18/294)

Reference group

 

≤8

50 (1/2)

15.33

0.057

 Infant sex N = 298

Male

5.5 (9/163)

Reference group

 

Female

7.4 (10/135)

1.37 (0.54–3.47)

0.509

 SGA N = 298

No

6.0 (15/249)

Reference group

 

Yes

8.2 (4/49)

1.39 (0.44–4.37)

0.577

 EGA at birth N = 298

≥ 39 wks

6.2 (14/226)

Reference group

 

37- < 39 wks

6.9 (5/72)

1.13 (0.39–3.25)

0.821

 Year of birth N = 298

2013–2015

6.7 (12/180)

Reference group

 

2016–2018

5.9 (7/118)

0.88 (0.34–2.31)

0.800

 Complicated/ difficult operative procedure N = 298

No

5.9 (16/273)

Reference group

 

Yes

12.0 (3/25)

2.19 (0.59–8.10)

0.240

 Postpartum day of tubal ligation N = 298

0–2

5.6 (12/216)

Reference group

 

3–7

8.5 (7/82)

1.59 (0.60–4.18)

0.350

  1. Abbreviations: CSWL clinically significant weight loss, EGA estimated gestational age, IV intravenous, PO per oral
  2. amedian [range]