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Table 2 Maternal complications of a second CD for women of different age ranges at the first CD

From: Maternal age at first cesarean delivery related to adverse pregnancy outcomes in a second cesarean delivery: a multicenter, historical, cross-sectional cohort study

Variables

Age

N (%)

OR (95%CI)

Model 1

Model 2

PAS

18–24

226 (8.3)

1.391 (1.17–1.66)

1.369 (1.15–1.63)

1.499 (1.12–2.01)

25–29

339 (6.1)

1

1

1

30–34

103 (5.9)

0.956 (0.76–1.20)

0.888 (0.70–1.12)

0.815 (0.59–1.12)

≥35

25 (11.4)

1.961 (1.28–3.02)

1.387 (0.88–2.18)

1.149 (0.59–2.24)

PP

18–25

390 (14.4)

1.322 (1.15–1.51)

1.335 (1.16–1.53)

1.349 (1.07–1.70)

25–29

623 (11.3)

1

1

1

30–34

193 (11)

0.975 (0.82–1.16)

0.879 (0.74–1.05)

0.87 (0.68–1.11)

≥35

36 (16.4)

1.539 (1.07–2.22)

1.063 (0.72–1.56)

1.04 (0.61–1.78)

Placental abruption

18–24

31 (1.1)

1.32 (0.84–2.08)

1.356 (0.86–2.14)

0.793 (0.37–1.69)

25–29

48 (0.9)

1

1

1

30–34

19 (1.1)

1.251 (0.73–2.14)

1.252 (0.73–2.16)

2.055 (0.95--4.44)

≥35

4 (1.8)

2.113 (0.76–5.91)

2.202 (0.76–6.38)

6.464 (1.33–31.51)

Abnormal amniotic fluid

18–24

299 (11)

1.075 (0.93–1.25)

1.108 (0.96–1.29)

0.974 (0.76–1.25)

25–29

571 (10.3)

1

1

1

30–34

165 (9.4)

0.902 (0.75–1.08)

0.823 (0.68–0.99)

0.932 (0.72–1.21)

≥35

20 (9.1)

0.867 (0.54–1.39)

0.73 (0.46–1.17)

0.971 (0.52–1.81)

Hypertension

18–24

296 (10.9)

1.08 (0.93–1.25)

1.093 (0.94–1.27)

1.044 (0.82–1.34)

25–29

563 (10.2)

1

1

1

30–34

190 (10.9)

1.073 (0.90–1.28)

1.022 (0.86–1.22)

1.076 (0.83–1.39)

≥35

32 (14.5)

1.5 (1.02–2.20)

1.297 (0.87–1.93)

1.456 (0.83–2.57)

DM

18–24

579 (21.4)

0.853 (0.76–0.95)

0.827 (0.74–0.93)

1.091 (0.91–1.31)

25–29

1334 (24.1)

1

1

1

30–34

485 (27.7)

1.203 (1.07–1.36)

1.275 (1.13–1.44)

0.976 (0.81–1.17)

≥35

72 (32.7)

1.528 (1.15–2.04)

1.63 (1.21–2.19)

0.907 (0.60–1.37)

PROM

18–24

333 (12.3)

0.915 (0.80–1.05)

0.918 (0.80–1.06)

0.905 (0.78–1.05)

25–29

733 (13.3)

1

1

1

30–34

238 (13.6)

1.028 (0.88–1.20)

1.013 (0.86–1.19)

1.022 (0.87–1.20)

≥35

42 (19.1)

1.542 (1.09–2.18)

1.529 (1.07–2.18)

1.556 (1.08–2.24)

ICP

18–24

37 (1.4)

1.946 (1.24–3.06)

1.927 (1.23–3.03)

1.947 (1.24–3.07)

25–29

39 (0.7)

1

1

1

30–34

11 (0.6)

0.889 (0.45–1.74)

0.897 (0.46–1.76)

0.892 (0.45–1.76)

≥35

2 (0.9)

1.29 (0.31–5.38)

1.317 (0.32–5.49)

1.321 (0.31–5.65)

ITP

18–24

55 (2)

1.465 (1.03–2.08)

1.565 (1.10–2.22)

1.057 (0.70–1.60)

25–29

77 (1.4)

1

1

1

30–34

15 (0.9)

0.611 (0.35–1.07)

0.528 (0.30–0.99)

0.779 (0.44–1.39)

≥35

1 (0.5)

0.323 (0.05–2.33)

0.246 (0.03–1.79)

0.58 (0.08–4.34)

Thyroid disease

18–24

69 (2.5)

0.651 (0.49–0.86)

0.632 (0.48–0.83)

1.031 (0.68–1.57)

25–29

213 (3.9)

1

1

1

30–34

88 (5)

1.319 (1.02–1.70)

1.406 (1.08–1.82)

0.907 (0.61–1.35)

≥35

12 (5.5)

1.439 (0.79–2.62)

1.605 (0.88–2.94)

0.633 (0.26–1.57)

  1. PAS Placenta accreta spectrum disorders, PP Placenta previa, DM Diabetes mellitus, PROM Premature rupture of membranes, ICP Intrahepatic cholestasis of pregnancy, ITP Idiopathic thrombocytopenic purpura, OR Odds ratios, CI Confidence interval
  2. Model 1: adjusted factors included gravidity, parity, BMI, ART, and interval months
  3. Model 2: adjusted factors included gravidity, parity, BMI, ART, interval months, and maternal age at second CD
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