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Table 4 Reclassification and Discrimination Statistics of adverse maternal and perinatal outcomes based on SBP trajectory

From: Gestational systolic blood pressure trajectories and risk of adverse maternal and perinatal outcomes in Chinese women

Clinical outcomes Model C statistics Continuous NRI, % IDI, %
Estimate (95% CI) P value Estimate (95% CI) P value Estimate (95% CI) P value
GH Model 3 0.835 (0.818 to 0.852)   Reference   Reference  
Model 3+ trajectory categories 0.859 (0.844 to 0.874) < 0.001 14.25 (0.53 to 0.68) < 0.001 2.98 (0.002 to 0.01) 0.003
PTD Model 4 0.833 (0.823 to 0.842)   Reference   Reference  
Model 4+ trajectory categories 0.834 (0.824 to 0.843) 0.151 4.76 (0.09 to 0.22) < 0.001 2.63 (0.0002 to 0.002) 0.009
ETD Model 4 0.665 (0.657 to 0.673)   Reference   Reference  
Model 4+ trajectory categories 0.666 (0.658 to 0.674) 0.038 2.83 (0.01 to 0.07) < 0.001 4.36 (0.001 to 0.002) < 0.001
SGA Model 4 0.655 (0.642 to 0.668)   Reference   Reference  
Model 4+ trajectory categories 0.657 (0.643 to 0.670) 0.171 3.12 (0.03 to 0.13) 0.002 2.94 (0.0002 to 0.001) 0.003
LBW Model 4 0.665 (0.657 to 0.658)   Reference   Reference  
Model 4+ trajectory categories 0.666 (0.658 to 0.674) 0.038 3.59 (0.08 to 0.26) 0.0003 2.77 (0.0004 to 0.002) 0.006
  1. NRI net reclassification improvement, IDI integrated discrimination index, CI confidence interval, GH gestational hypertension, ETD early-term delivery, PTD pre-term delivery, SGA small for gestational age, LBW low birth weight
  2. Model 3 included maternal age at delivery (in years, continuous), early pregnancy BMI (Kg/m2, continuous), gestation, parity, presence of GDM, SBP (mmHg, continuous) at the first visit, and SBP measurement times (continuous) during pregnancy;
  3. Model 4 was additionally controlled for infant sex (boys, girls) and presence of hypertensive disorders in pregnancy (including GH, PE and eclampsia), on the basis of Model 3
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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