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Table 4 Association of independent variables with postpartum hemorrhage adjusted for anti-thyroid peroxidase (Anti-TPO) and anti-thyroglobulin (Anti-TG) antibodies on multivariate logistic regression

From: Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4)

  Unadjusted OR (95% CI) P-value Adjusted OR (95% CI) P-value Unadjusted OR (95% CI) P-value Adjusted OR (95% CI) P-value
ANTI-THYROID PEROXIDASE ANTI-THYROGLOBULIN
Positive 1   1   1   1  
Negative 1.46 (0.72–2.99) 0.29 1.56 (0.35–1.92) 0.21 1.36 (0.68–2.69) 0.88 1.45 (0.83–3.16) 0.74
AGE GROUPS
Age 20–25 1     1    
Age 26–30 1.07 (0.32–3.5) 0.11    1.07 (0.32–3.5) 0.11   
Age 31–35 0.85 (0.23–2.87)    0.85 (0.23–2.87)   
Age 36 and above 2.8(0.74–10.47)    2.8(0.74–10.47)   
PARITY
Nulliparous 1     1    
Primiparous 0.68 (0.38–1.62) 0.60    0.68 (0.38–1.62) 0.60   
Biparous/multiparous 1.01 (0.44–2.29)   1.01 (0.44–2.29)  
BODY MASS INDEX
Underweight/Normal 1 0.253    1 0.253   
Overweight/obese 1.53 (0.73–3.17)    1.53 (0.73–3.17)   
PRE GESTATIONAL DIABETES
Yes 1.91 (0.45–8.02) 0.373    1.91 (0.45–8.02) 0.373   
No 1    1   
GESTATIONAL DIABETES
Yes 3.84 (1.64–9.28) 0.03 3.35 (2.61–4.21) 0.01* 3.84 (1.64–9.28) 0.03 2.38 (1.54–3.45) 0.012*
No 1 1   1 1
HYPERTENSION
No 1   1   1   1  
Pre-eclampsia/ Gestational Hypertension 2.68 (1.32–4.07) 0.01 2.82 (2.02–4.16) 0.04* 2.68 (1.32–4.07) 0.01 3.01 (2.14–4.27) 0.029*
Chronic Hypertension 5.36 (1.31–21.87) 3.21 (1.59–4.56) 5.36 (1.31–21.87) 3.21 (1.59–4.56)
  1. *Fischer test applied. P-value significant at <=0.05