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Table 1 Association of thyroid antibodies with baseline characters in hypothyroid pregnancies

From: Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4)

 

Anti-TPO

P value

Anti-TG

P value

Positive

N (%)

N = 97

Negative

N (%)

N = 49

Positive

N (%)

N = 76

Negative

N (%)

N = 70

Age Groups

 Age 20–25

8 (8.2)

8 (16.3)

 

8 (10.5)

8 (11.4)

 

 Age 26–30

41 (42.3)

20 (40.8)

0.243

27 (35.5)

34 (48.6)

0.363

 Age 31–35

28 (28.9)

16 (32.7)

 

27 (35.5)

17 (24.3)

 

 Age 36 and above

20 (20.6)

5 (10.2)

 

14 (18.4)

11 (15.7)

 

Paritya

 Nulliparous

30 (31.9)

20 (42.6)

0.213

22 (29.7)

28 (41.8)

0.135

 Multiparous

64 (68.1)

27 (57.4)

 

52 (70.3)

39 (58.2)

 

BMI

 Underweight (< 18.5)

4 (4.7)

2 (4.7)

 

3 (4.6)

3 (4.7)

 

 Normal (18.5–24.9)

33 (38.4)

13 (30.2)

 

25 (38.5)

21 (32.8)

 

 Overweight (25–29.9)

30 (34.9)

15 (34.9)

0.826b

25 (38.5)

20 (31.2)

0.565b

 Obesity class I (30–34.9)

16 (18.6)

11 (25.6)

 

10 (15.4)

17 (26.6)

 

 Obesity class II and above (> = 35)

3 (3.5)

2 (4.7)

 

2 (3.1)

3 (4.7)

 

Pre-Gestational Diabetes

 Yes

2 (2.1)

6 (12.2)

0.018b

2 (2.7)

6 (8.6)

0.155b

 No

94 (97.9)

43 (87.8)

 

73 (97.3)

64 (91.4)

 

Gestational Diabetes

 Yes

21 (21.9)

5 (10.2)

0.083

12 (16.0)

14 (20.0)

0.530

 No

75 (78.1)

44 (89.8)

 

63 (84.0)

56 (80.0)

 

Hypertension

 No

84 (87.5)

38 (77.6)

 

65 (86..7)

57 (81.4)

 

 Gestational Hypertension/Pre-eclampsia

6 (6.2)

7 (14.3)

0.248b

4 (5.3)

9 (12.9)

0.250b

 Chronic Hypertension

6 (6.2)

4 (8.2)

 

6 (8.0)

4 (5.7)

 
  1. Anti-TPO anti-thyroid peroxidase antibodies, Anti-TG anti-thyroglobulin antibodies, BMI Body mass index. P-values calculated by Chi-square test applied. aData of 5 cases are missing. bFischer exact test applied