Skip to main content

Table 1 Association of thyroid antibodies with baseline characters in hypothyroid pregnancies

From: Association of thyroid antibodies status on the outcomes of pregnant women with hypothyroidism (maternal hypothyroidism on pregnancy outcomes, MHPO-4)

  Anti-TPO P value Anti-TG P value
Positive
N (%)
N = 97
Negative
N (%)
N = 49
Positive
N (%)
N = 76
Negative
N (%)
N = 70
Age Groups
 Age 20–25 8 (8.2) 8 (16.3)   8 (10.5) 8 (11.4)  
 Age 26–30 41 (42.3) 20 (40.8) 0.243 27 (35.5) 34 (48.6) 0.363
 Age 31–35 28 (28.9) 16 (32.7)   27 (35.5) 17 (24.3)  
 Age 36 and above 20 (20.6) 5 (10.2)   14 (18.4) 11 (15.7)  
Paritya
 Nulliparous 30 (31.9) 20 (42.6) 0.213 22 (29.7) 28 (41.8) 0.135
 Multiparous 64 (68.1) 27 (57.4)   52 (70.3) 39 (58.2)  
BMI
 Underweight (< 18.5) 4 (4.7) 2 (4.7)   3 (4.6) 3 (4.7)  
 Normal (18.5–24.9) 33 (38.4) 13 (30.2)   25 (38.5) 21 (32.8)  
 Overweight (25–29.9) 30 (34.9) 15 (34.9) 0.826b 25 (38.5) 20 (31.2) 0.565b
 Obesity class I (30–34.9) 16 (18.6) 11 (25.6)   10 (15.4) 17 (26.6)  
 Obesity class II and above (> = 35) 3 (3.5) 2 (4.7)   2 (3.1) 3 (4.7)  
Pre-Gestational Diabetes
 Yes 2 (2.1) 6 (12.2) 0.018b 2 (2.7) 6 (8.6) 0.155b
 No 94 (97.9) 43 (87.8)   73 (97.3) 64 (91.4)  
Gestational Diabetes
 Yes 21 (21.9) 5 (10.2) 0.083 12 (16.0) 14 (20.0) 0.530
 No 75 (78.1) 44 (89.8)   63 (84.0) 56 (80.0)  
Hypertension
 No 84 (87.5) 38 (77.6)   65 (86..7) 57 (81.4)  
 Gestational Hypertension/Pre-eclampsia 6 (6.2) 7 (14.3) 0.248b 4 (5.3) 9 (12.9) 0.250b
 Chronic Hypertension 6 (6.2) 4 (8.2)   6 (8.0) 4 (5.7)  
  1. Anti-TPO anti-thyroid peroxidase antibodies, Anti-TG anti-thyroglobulin antibodies, BMI Body mass index. P-values calculated by Chi-square test applied. aData of 5 cases are missing. bFischer exact test applied