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Table 3 Association of adverse neonatal outcomes with their positive and negative predictive values for the INTERGROWTH and WHO criteria. GROW: gestation related optimum weight; NICU: neonatal intensive care unit; WHO: world health organisation. Composite outcome: birth injury, neonatal hypoglycaemia, hyperbilirubinaemia, respiratory distress syndrome, or neonatal intensive care admission; sen: sensitivity; spe: specificity; ppv: positive predictive value; npv: negative predictive value

From: Which growth standards should be used to identify large- and small-for-gestational age infants of mothers with type 1 diabetes? A pre-specified analysis of the CONCEPTT trial

  Caesarean delivery Preterm delivery Neonatal hypoglycaemia NICU Admission Hyperbilirubinaemia Respiratory Distress Composite Outcome
sen spe ppv npv sen spe ppv npv sen spe ppv npv sen spe ppv npv sen spe ppv npv sen spe ppv npv sen spe ppv npv
Birthweight > 84.1st centile (mean + 1 sd)
 GROW > 84.1st centile 71 49 75 43 66 36 40 62 75 39 29 82 72 39 41 71 74 39 32 80 79 36 10 95 73 42 53 63
 INTERGROWTH > 84.1st centile 81 40 75 48 75 26 40 62 81 28 28 81 77 27 38 67 77 27 29 76 79 26 9 93 78 29 50 59
 WHO > 84.1st centile 43 77 80 38 22 54 24 52 44 66 30 78 36 63 37 63 31 61 23 70 32 63 7 91 36 64 48 52
Birthweight >90th centile (mean + 1.28 sd)
 GROW >90th centile 68 51 76 42 66 40 42 65 75 42 31 84 71 43 42 72 73 42 32 80 79 39 11 95 72 47 55 65
 INTERGROWTH >90th centile 72 46 75 43 66 33 39 60 77 37 29 83 75 38 41 72 74 36 31 79 79 34 10 95 74 40 53 63
 WHO >90th centile 36 84 84 37 17 62 22 53 39 73 33 78 30 70 37 63 26 69 24 71 21 69 6 91 31 71 49 53
Birthweight > 97.7th centile (mean + 2 sd)
 GROW > 97.7th centile 50 76 82 41 51 63 47 66 63 65 38 84 54 65 47 71 53 62 35 78 58 59 12 94 52 67 59 61
 INTERGROWTH > 97.7th centile 48 76 82 40 43 60 41 62 61 66 38 83 51 65 46 69 45 61 30 74 53 60 11 93 50 67 58 59
 WHO > 97.7th centile 14 90 75 32 9 85 29 59 25 92 50 78 18 91 54 65 11 87 25 72 16 88 11 92 16 91 61 54
 GROW <10th centile 3 99 80 31 3 99 60 61 2 98 20 75 4 99 60 64 5 99 60 73 5 98 20 92 3 98 60 53
 INTERGROWTH <10th centile 2 100 100 32 2 99 67 61 0 98 0 74 2 99 67 64 3 99 67 73 5 99 33 92 2 99 67 53
 WHO <10th centile 10 94 80 32 18 97 80 64 11 92 30 75 16 95 65 66 15 93 45 74 26 93 25 93 14 96 75 55
 GROW <25th centile 7 97 85 32 8 96 54 61 4 93 15 74 6 94 38 63 8 95 38 73 11 95 15 92 5 93 38 52
 INTERGROWTH <25th centile 3 97 71 31 4 98 57 61 2 96 14 74 5 98 57 64 6 98 57 73 11 98 29 92 4 97 57 53
 WHO <25th centile 18 87 76 32 31 93 76 68 19 85 30 76 27 89 59 68 26 87 43 76 37 85 19 94 24 91 70 57