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Table 2 Association between coffee consumption frequency and the risk of bleeding in early pregnancy according to age (n = 3510)

From: Maternal coffee intake and the risk of bleeding in early pregnancy: a cross-sectional analysis

 

Total No.

No. (%)

Unadjusted OR (95% CI)

Adjusted OR (95% CI)a

Overall

3510

636(18.1)

  

 Seldom coffee drinkers

1077

173(16.1)

1.000

1.000

 Light coffee drinkers (< 1 cup/day)

595

103(17.3)

1.094(0.837–1.429)

1.086(0.827–1.425)

 Moderate coffee drinkers (1 cup/day)

1202

226(18.8)

1.210(0.973–1.504)

1.225(0.981–1.530)

 Heavy coffee drinkers (≥2 cups/day)

636

134(21.1)

1.395(1.086–1.792)

1.358(1.050–1.757)

Aged < 35 years

2214

372(16.8)

  

 Seldom coffee drinkers

729

111(15.2)

1.000

1.000

 Light coffee drinkers (< 1 cup/day)

383

57(14.9)

0.973(0.688–1.376)

0.993(0.699–1.411)

 Moderate coffee drinkers (1 cup/day)

747

125(16.7)

1.119(0.847–1.479)

1.163(0.875–1.547)

 Heavy coffee drinkers (≥2 cups/day)

355

79(22.3)

1.594(1.155–2.198)

1.680(1.207–2.338)

Aged ≥35 years

1296

264(20.4)

  

 Seldom coffee drinkers

348

62(17.8)

1.000

1.000

 Light coffee drinkers (< 1 cup/day)

212

46(21.7)

0.973(0.688–1.376)

1.278(0.834–1.958)

 Moderate coffee drinkers (1 cup/day)

455

101(22.2)

1.119(0.847–1.479)

1.316(0.925–1.872)

 Heavy coffee drinkers (≥2 cups/day)

281

55(19.6)

1.594(1.155–2.198)

1.123(0.750–1.679)

  1. aadjusted for age, body mass index, systolic blood pressure, cigarette smoking and alcohol consumption behavior, previous and current physical activity levels, stress levels, history of depression, presence of antenatal depressive symptoms during the first trimester, type of emesis, parity, and the number of livebirths, stillbirths, miscarriages, and abortions