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Table 3 Odds ratios of adverse birth outcomes after cholecystectomy before pregnancy

From: Appendectomy, cholecystectomy and diagnostic laparoscopy conducted before pregnancy and risk of adverse birth outcomes: a nationwide registry-based prevalence study 1996–2015

Outcome

Months from cholecystectomy to LMP

Cholecystectomy 0–11 months before LMP

Cholecystectomy 12–23 months before LMP

 

0–11

12–23

24+

 

N (%)

N (%)

N (%)

cOR (95% CI)

aOR* (95% CI)

cOR (95% CI)

aOR* (95% CI)

SGA

75/2950 (2.5)

47/2243 (2.1)

181/7676 (2.4)

1.1 (0.8;1.4)

1.1 (0.8;1.5)

0.9 (0.6;1.2)

0.9 (0.6;1.2)

Preterm

 Early preterm

29/2950 (1.0)

24/2243 (1.1)

68/7676 (0.9)

1.1 (0.7;1.7)

1.1 (0.7;1.8)

1.2 (0.8;1.9)

1.2 (0.8;2.0)

 Late preterm

108/2950 (3.7)

103/2243 (4.6)

364/7676 (4.7)

0.8 (0.6;1.0)

0.8 (0.6;1.0)

1.0 (0.8;1.2)

1.0 (0.8;1.2)

Miscarriage

227/2950 (7.7)

136/2243 (6.1)

526/7676 (6.9)

1.1 (1.0;1.3)

1.3 (1.1;1.5)

0.9 (0.7;1.1)

1.0 (0.8;1.2)

  1. *Adjusted for smoking status and maternal age, miscarriage only adjusted for maternal age
  2. Legend: Prevalence, crude and adjusted odds ratios (cOR/aOR) of small for gestational age (SGA), early preterm birth, late preterm birth and miscarriage in pregnancies with cholecystectomy before pregnancy