First-trimester maternal serum alpha-fetoprotein is not a good predictor for adverse pregnancy outcomes: a retrospective study of 3325 cases

Table 3 The performance of MS-AFP for the subdivisions of adverse pregnancy outcomes

APOs	n	AUROC	P value
Total preeclampsia	81	0.579	0.015
Severe preeclampsia	36	0.585	0.079
Total preterm birth	181	0.572	0.001
Preterm birth at < 32 weeks	19	0.551	0.456
Spontaneous preterm birth	145	0.556	0.023
Iatrogenic preterm birth	36	0.631	0.007
Total SGA (< 10th percentile)	362	0.565	0.000
Severe SGA (< 3rd percentile)	89	0.604	0.001
FGR	104	0.602	0.000

APOs Adverse pregnancy outcomes, SGA Small for gestational age, FGR Fetal growth restriction by ultrasound definition put forward by Gordijn et al. [21], AUROC Area under ROC curve

ISSN: 1471-2393