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Table 1 Clinical variables of women with GDM and normal glucose regulation in third trimester pregnancy

From: Gestational diabetes and the human salivary microbiota: a longitudinal study during pregnancy and postpartum

 GDM (n = 50)Normoglycaemic (n = 161)P
Descriptive measurements
 Age (years)34.4 (4.4)33.3 (4.6)0.1
 Gestational age at examination (weeks)28.7 (1.4)28.4 (1.1)0.1
 Systolic BP (mmHg)118 (11.2)111 (10.6)0.001
 Diastolic BP (mmHg)71 (8.1)67 (8.5)0.001
 Height (cm)168.6 (6.6)169.7 (5.6)0.2
 Weight (kg)91.8 (14.1)87.3 (14.6)0.06
 Pre-pregnancy weight (kg) (n = 190)83.5 (16.0) (n = 43)78.5 (15.2) (n = 145)0.06
 Pre-pregnancy BMI kg/m2(n = 189)29.3 (5.6) (n = 43)27.1 (4.8) (n = 144)0.02
 Weight gain (kg) (n = 188)7.4 (4.7) (n = 43)8.8 (7.5) (n = 145)0.3
Biochemistry at 75 g OGTT
 Plasma glucose at time 0 min (mmol/L)5.2 (0.4)4.6 (0.2)5.8 × 10−31
 Plasma gucose at time 30 min (mmol/L)8.1 (1.0)6.9 (0.9)2.7 × 10−12
 Plasma glucose at time 60 min (mmol/L)8.9 (1.3)7.1 (1.2)1.9 × 10− 15
 Plasma glucose at time 120 min (mmol/L)7.9 (1.4)6.2 (1.0)5.0 × 10−17
 Plasma insulin at time 0 min (pmol/L)112.1 (41)82.7 (40)3.3 × 10−5
 Plasma insulin at time 30 min (pmol/L)a509 (228)513 (349)0.7
 Plasma insulin at time 60 min (pmol/L)a743 (476)569 (448)0.058
 Plasma insulin at time 120 min (pmol/L)a769 (640)479 (320)6.3 × 10− 6
 HbA1c (mmol/mol)34.0 (3.1)33.0 (2.8)0.02
 HOMA-IR2.1 (0.8)1.5 (0.7)1.3 × 10− 6
 Matsuda index3.5 (1.5)5.3 (1.6)3.0 × 10− 8
 Disposition index4.1 (1.6)7.8 (1.6)9.2 × 10− 12
 Insulinogenic Index1.2 (1.6)1.5 (1.6)0.004
 Plasma hsCRP (mg/L)4.4 (1.9)3.8 (2.2)0.2
  1. Data presented as mean (standard deviation) or as amedian (interquartile range). For continuous variables P was calculated by two-tailed t-test and for categorical variables P was calculated by chi square test or Fisher’s exact test. BMI Body Mass Index, BP Blood pressure, GA Gestational age, HbA1c Glycated haemoglobin, HOMA-IR Homeostatic model of insulin resistance, hsCRP High sensitive C-reactive protein