G-Computation estimate | Total effect β (95%CI) | p | Natural direct effect β (95%CI) | p | Natural indirect effect β (95%CI) | p | Mediated effect (%) |
---|---|---|---|---|---|---|---|
Gestational age at delivery (weeks) | −1.29 (−2.22; −0.38) | 0.006* | −0.10 (−0.82; 0.63) | 0.79 | −1.20 (−2.04; − 0.36) | 0.005* | 92% |
Birthweight (g) | − 302.2 (− 593.7; − 10.7) | 0.04* | 27.8 (− 145.6; 201.2) | 0.75 | − 330.1 (−571.3; −88.8) | 0.007* | 92% |
Length at birth (cm) | − 0.82 (− 1.79; 016) | 0.10 | 0.06 (− 0.59; 0.71) | 0.85 | − 0.88 (− 1.50; − 0.26) | 0.006* | 94% |
Head circumference at birth (cm) | − 0.82 (− 1.78; 0.15) | 0.10 | 0.05 (− 0.60; 0.70) | 0.88 | − 0.87 (− 1.49; − 0.24) | 0.006* | 95% |