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Table 3 Child- health outcomes from spontaneous pregnancy and assisted reproductive technology (ART). The 2015 Pelotas (Brazil) Birth Cohort Study

From: Maternal and child-health outcomes in pregnancies following Assisted Reproductive Technology (ART): a prospective cohort study

 

Total pregnancies

Singleton pregnancies

Multiple pregnancies

Spontaneous

n = 4252

ART

n = 23

 

Spontaneous

n = 4150

ART

n = 14

 

Spontaneous

n = 102

ART

n = 9

 
 

mean

SD

mean

SD

pa

mean

SD

mean

SD

pa

mean

SD

mean

SD

pa

Gestational age at delivery (weeks)

38.5

2.3

36.9

2.0

0.001*

38.6

2.2

37.9

1.5

0.25

34.2

3.0

35.3

1.8

0.30

1-min Apgar

8.4

1.6

8.4

2.0

0.83

8.4

1.6

9.1

0.9

0.08

7.2

2.1

7.3

2.7

0.88

5-min Apgar

9.4

0.9

9.4

0.9

0.94

9.5

0.9

9.7

0.5

0.28

8.7

1.7

9.0

1.2

0.55

Birthweight (g)

3.171

563

2.832

699

0.004*

3.197

537

3.251

474

0.71

2.070

531

2.178

438

0.55

Length at birth (cm)

48

2.7

46

3.3

< 0.001*

48

2.6

48

1.9

0.71

43

3.4

43

2.4

0.71

Head circumference at birth (cm)

34

1.9

33

2.3

0.06

34

1.9

34

1.4

0.32

31

2.1

31

1.7

0.95

Breastfeeding up to 12 months (days)

223

141

227

151

0.88

226

141

300

106

0.05

96

93.4

114

144

0.60

 

n

%

n

%

pb

n

%

n

%

pb

n

%

n

%

pb

Preterm birth (< 37 weeks)

655

15.4

8

34.8

0.01*

574

13.8

2

14.3

1.00

81

79.4

6

66.7

0.40

Breastfeeding at 12 months

1692

42.4

11

47.8

0.60

1687

43.2

9

64.3

0.18

5

5.6

2

22.2

0.12

Intrauterine growth restriction (IUGR)

644

15.3

5

21.7

0.38

611

14.8

1

7.1

0.42

33

34.2

4

44.4

0.72

Health complications at birth

458

10.8

5

21.7

0.09

412

10.0

1

7.1

0.73

46

46.9

4

44.4

0.89

  1. aStudent’s T-test. bFisher’s exact test. ART assisted reproductive technology, BMI body mass index. *p < 0.05