A novel association of CCDC80 with gestational diabetes mellitus in pregnant women: a propensity score analysis from a case-control study

Table 2 Clinical cardiometabolic parameters of study participants

Variables	All cases			Propensity score-matched sets
Variables	Control (n = 252)	GDM (n = 61)	P value	Control (n = 122)	GDM (n = 61)	P value
ALT (U/L)	10.33 ± 7.93	9.98 ± 5.35	0.744	9.33 ± 6.63	9.98 ± 5.35	0.503
AST (U/L)	12.60 ± 6.62	11.28 ± 5.21	0.146	12.04 ± 5.61	11.28 ± 5.21	0.376
MAO (U/L)	7.43 ± 2.47	6.98 ± 2.18	0.188	7.60 ± 2.58	6.98 ± 2.18	0.110
Creatinine (umol/L)	37.41 ± 19.62	36.71 ± 7.30	0.784	38.88 ± 27.26	36.71 ± 7.30	0.543
Hemoglobin (g/L)	126.17 ± 13.4	129.18 ± 13.0	0.113	126.34 ± 14.5	129.18 ± 13.0	0.199
Inflammatory marker
WBC count (× 10⁹/L)	8.74 ± 6.88	8.00 ± 1.94	0.412	8.75 ± 7.35	8.00 ± 1.94	0.435
IL-6 (pg/mL)	2.23 ± 0.90	2.45 ± 0.83	0.074	2.21 ± 0.93	2.45 ± 0.83	0.084
CRP (mg/L)	4.67 ± 3.21	5.22 ± 2.69	0.226	4.90 ± 3.00	5.22 ± 2.69	0.488
Complement C1q (mg/L)	158.5 ± 37.5	157.4 ± 34.4	0.824	163.1 ± 37.5	157.4 ± 34.4	0.322
Lipids
Triglyceride (mmol/L)	1.85 ± 0.85	2.24 ± 1.41	0.006^*	2.01 ± 0.97	2.24 ± 1.41	0.197
Cholesterol (mmol/L)	4.39 ± 1.09	4.78 ± 3.92	0.170	4.42 ± 1.08	4.78 ± 3.92	0.346
HDL-C (mmol/L)	1.44 ± 0.42	1.35 ± 0.44	0.146	1.43 ± 0.40	1.35 ± 0.44	0.214
LDL-C (mmol/L)	2.38 ± 0.77	2.22 ± 0.80	0.153	2.37 ± 0.76	2.22 ± 0.80	0.201
Apolipoprotein A1 (g/L)	1.60 ± 0.42	1.58 ± 0.42	0.790	1.62 ± 0.42	1.58 ± 0.42	0.528
Apolipoprotein B (g/L)	0.81 ± 0.24	0.80 ± 0.26	0.782	0.83 ± 0.24	0.80 ± 0.26	0.499

WBC white blood cell, IL-6 interleukin-6, CRP C-reaction protein, ALT alanine aminotransferase, AST Aspartic aminotransferase, MAO monoamine oxidase, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol
*P < 0.05

ISSN: 1471-2393