Single-course antenatal corticosteroids is related to faster growth in very-low-birth-weight infant

Table 2 Multivariate analysis of ACS courses association with nutritional outcomes in VLBW infants stratified by GA

Variable	Total		28 weeks ≤ GA < 32 weeks
Variable	Single-course ACS	Repeated course ACS	Single-course ACS	Repeated course ACS
Amino acid introduction^a	−0.11 (− 0.70, − 0.15) *	−0.05 (−0.44,0.04)	−0.09 (−0.71, −0.04) *	−0.04 (−0.44,0.14)
Lipid introduction^b	−0.04 (1.42,0.38)	−0.05 (− 1.35,0.23)	− 0.02 (−1.46,0.76)	− 0.05 (− 1.57,0.34)
Enteral nutrition introduction^c	−0.08 (−1.35, − 0.11) *	− 0.04 (− 0.87,0.22)	−0.09 (− 1.52, − 0.01) *	− 0.05 (− 1.08,0.22)
Enteral feeding volumes of 150 mL·kg^− 1·d^-1d	− 0.03 (−3.70,0.94)	0.006 (− 1.89,2.30)	− 0.03 (− 4.22,1.50)	0.009 (− 2.24,2.84)

Data are adjusted linear regression coefficient (95% CI), refer to non-ACS
VLBW very-low-birth-weight, ACS Antenatal corticosteroids, GA gestational age
*multiple linear regression shows significant outcomes. No significant outcomes were found in GA < 28 weeks or 32 weeks ≤ GA < 37 weeks group
^a adjusted for GA, 5 min APGAR score
^b adjusted for GA, 5 min APGAR score and amino acid introduction
^c adjusted for GA, birth weight, cesarean section, lipid introduction and amino acid introduction
^d adjusted for GA, birth weight, cesarean section, lipid introduction, amino acid introduction and feeding pattern

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