Obstetric and neonatal outcomes in women with pregnancy associated cancer: a population-based study in Lombardy, Northern Italy

Table 2 Adverse obstetric outcomes among 831 women with pregnancy associated cancer (PAC) and 3324 matched cancer-free women. Lombardy, Italy. 2008–2017

	Labor induction or planning of delivery ^a (Induced or elective CS Vs Spontaneous)			Mode of delivery ^b (Emergency or elective CS Vs vaginal or instrumental)			Timing of delivery (Very low, low, moderate or late preterm ^c Vs at term)
	N (%) of events	PR (95% CI)	aPR (95% CI)	N (%) of events	PR (95% CI)	aPR (95% CI)	N (%) of events	PR (95% CI)	aPR (95% CI)
Cancer-free	299 (40.9)	1^d	1^d	226 (30.4)	1^d	1^d	48 (6.5)	1^d	1^d
PAC during pregnancy	139 (76.0)	1.86 (1.65–2.10)	1.80 (1.57–2.07)	100 (54.0)	1.78 (1.50–2.11)	1.78 (1.49–2.11)	77 (41.4)	6.42 (4.65–8.86)	6.34 (4.59–8.75)
Cancer-free	1027 (40.3)	1^d	1^d	807 (31.5)	1^d	1^d	198 (7.7)	1^d	1^d
PAC post-pregnancy	283 (44.2)	1.10 (0.99–1.21)	1.08 (0.98–1.20)	209 (32.6)	1.03 (0.91–1.15)	1.03 (0.91–1.17)	61 (9.5)	1.23 (0.94–1.62)	1.18 (0.90–1.55)

PR Prevalence ratio; aPR adjusted Prevalence Ratio; CI Confidence Intervals; CS Cesarean Section; PAC Pregnancy Associated Cancer
^aWere excluded from the analysis 8 and 46 observations with missing values among PAC and non PAC women, respectively
^bWere excluded from the analysis 4 and 16 observations with missing values among PAC and non PAC women, respectively
^cVery low preterm birth: before 28th week, low preterm birth: between the 28th and the 32th week, moderate preterm birth: between the 32th and the 34th week, late preterm birth: between the 34th and the 37th week
^dReference category

ISSN: 1471-2393