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Table 4 Multivariable hazard ratios (HR) and 95% confidence intervals (CI) of incident CVD per additional parity among women: Tehran Lipid and Glucose Study, Iran, 1999–2016

From: Number of parity/live birth(s) and cardiovascular disease among Iranian women and men: results of over 15 years of follow-up

 

Model 1

Model 2

HR (95% CI)

p-value

HR (95% CI)

p-value

Parity (per each additional)

1.08 (1.04–1.13)

< 0.001

1.05 (1.01–1.10)

0.028

Age (year)

1.07 (1.06–1.08)

< 0.001

1.05 (1.03–1.06)

< 0.001

BMI (kg/m2)

  

1.01 (0.99–1.03)

0.415

T2DM, yes

  

2.36 (1.92–2.90)

< 0.001

Hypertension, yes

  

1.84 (1.49–2.26)

< 0.001

Hypercholesterolemia, yes

  

1.82 (1.38–2.41)

< 0.001

Low physical activity, yes

  

1.12 (0.91–1.39)

0.285

Educational levels

 Illiterate/primary school

  

Reference

 

 Below diploma/diploma

  

0.79 (0.59–1.05)

0.100

 Above diploma

  

0.68 (0.34–1.34)

0.267

Smoking status

 Never

  

Reference

 

 Former

  

1.09 (0.71–1.69)

0.686

 Current

  

1.65 (1.09–2.51)

0.017

FH of premature CVD, yes

  

1.62 (1.31–1.99)

< 0.001

History of miscarriage, yes

  

1.17 (0.97–1.41)

0.091

OCP use, yes

  

0.48 (0.20–1.18)

0.108

  1. BMI Body mass index, T2DM Type 2 diabetes mellitus, OCP Oral contraceptive pill, CVD Cardiovascular disease, FH Family history
  2. Model 1: adjusted for age
  3. Model 2: adjusted for age, BMI, T2DM, hypertension, hypercholesterolemia, educational levels, smoking status, family history of premature CVD, history of miscarriage, and OCP use
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BMC Pregnancy and Childbirth

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