Women | Men | |||||||
---|---|---|---|---|---|---|---|---|
Model 1 | Model 2 | Model 1 | Model 2 | |||||
HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | HR (95% CI) | p-value | |
Number of Live births | ||||||||
1 | Reference | Reference | Reference | Reference | ||||
2 | 0.89 (0.44–1.80) | 0.752 | 0.86 (0.43–1.73) | 0.676 | 2.00 (1.26–3.16) | 0.003 | 1.97 (1.24–3.12) | 0.004 |
3 | 1.57 (0.83–2.97) | 0.162 | 1.42 (0.75–2.70) | 0.279 | 2.25 (1.42–3.58) | 0.001 | 2.08 (1.31–3.31) | 0.002 |
≥ 4 | 2.17 (1.18–4.00) | 0.012 | 1.72 (0.92–3.21) | 0.087 | 2.20 (1.37–3.52) | 0.001 | 2.08 (1.30–3.34) | 0.002 |
Age (year) | 1.07 (1.06–1.08) | < 0.001 | 1.04 (1.03–1.06) | < 0.001 | 1.05 (1.04–1.06) | < 0.001 | 1.05 (1.04–1.06) | < 0.001 |
BMI (kg/m2) | 1.01 (0.98–1.03) | 0.613 | 1.01 (0.99–1.04) | 0.270 | ||||
T2DM, yes | 2.37 (1.93–2.91) | < 0.001 | 2.37 (1.89–2.96) | < 0.001 | ||||
Hypertension, yes | 1.83 (1.49–2.25) | < 0.001 | 1.56 (1.29–1.90) | < 0.001 | ||||
Hypercholesterolemia, yes | 1.80 (1.37–2.38) | < 0.001 | 1.47 (1.22–1.77) | < 0.001 | ||||
Low physical activity, yes | 1.13 (0.91–1.40) | 0.266 | 1.04 (0.85–1.26) | 0.728 | ||||
Educational levels | ||||||||
Illiterate/primary school | Reference | Reference | ||||||
Below diploma/diploma | 0.86 (0.64–1.14) | 0.284 | 1.14 (0.93–1.41) | 0.211 | ||||
Above diploma | 0.79 (0.40–1.57) | 0.503 | 0.96 (0.71–1.29) | 0.771 | ||||
Smoking status | ||||||||
Never | Reference | Reference | ||||||
Former | 1.11 (0.71–1.71) | 0.653 | 1.27 (1.01–1.60) | 0.039 | ||||
Current | 1.68 (1.11–2.55) | 0.014 | 1.60 (1.30–1.97) | < 0.001 | ||||
FH of premature CVD, yes | 1.62 (1.32–2.00) | < 0.001 | 1.33 (1.05–1.69) | 0.020 | ||||
History of miscarriage, yes | 1.17 (0.98–1.41) | 0.090 | ||||||
OCP use, yes | 0.50 (0.20–1.22) | 0.126 |