Skip to main content

Table 2 Multivariable hazard ratios (HR) and 95% confidence intervals (CI) of incident CVD per additional live birth among women and men: Tehran Lipid and Glucose Study, Iran, 1999–2016

From: Number of parity/live birth(s) and cardiovascular disease among Iranian women and men: results of over 15 years of follow-up

 

Women

Men

Model 1

Model 2

Model 1

Model 2

HR (95% CI)

p-value

HR (95% CI)

p-value

HR (95% CI)

p-value

HR (95% CI)

p-value

Live birth (per each additional)

1.07 (1.03–1.12)

0.002

1.04 (0.99–1.09)

0.094

1.02 (0.97–1.08)

0.474

1.01 (0.95–1.07)

0.714

Age (year)

1.07 (1.06–1.08)

< 0.001

1.05 (1.03–1.06)

< 0.001

1.06 (1.05–1.07)

< 0.001

1.06 (1.05–1.07)

< 0.001

BMI (kg/m2)

  

1.01 (0.99–1.03)

0.404

  

1.01 (0.99–1.04)

0.219

T2DM, yes

  

2.37 (1.92–2.91)

< 0.001

  

2.41 (1.92–3.01)

< 0.001

Hypertension, yes

  

1.84 (1.49–2.26)

< 0.001

  

1.55 (1.28–1.88)

< 0.001

Hypercholesterolemia, yes

  

1.82 (1.38–2.41)

< 0.001

  

1.49 (1.24–1.79)

< 0.001

Low physical activity, yes

  

1.12 (0.91–1.39)

0.282

  

1.03 (0.85–1.26)

0.735

Educational levels

 Illiterate/primary school

  

Reference

   

Reference

 

 Below diploma/diploma

  

0.78 (0.59–1.03)

0.084

  

1.14 (0.92–1.41)

0.229

 Above diploma

  

0.67 (0.34–1.32)

0.248

  

0.96 (0.71–1.29)

0.772

Smoking status

 Never

  

Reference

   

Reference

 

 Former

  

1.09 (0.71–1.69)

0.693

  

1.27 (1.01–1.59)

0.044

 Current

  

1.65 (1.09–2.50)

0.018

  

1.60 (1.30–1.96)

< 0.001

FH of premature CVD, yes

  

1.61 (1.31–1.99)

< 0.001

  

1.32 (1.04–1.68)

0.023

History of miscarriage, yes

  

1.18 (0.98–1.42)

0.088

    

OCP use, yes

  

0.48 (0.20–1.18)

0.109

    
  1. BMI Body mass index, T2DM Type 2 diabetes mellitus, OCP Oral contraceptive pill, CVD Cardiovascular disease, FH Family history
  2. Model 1: adjusted for age
  3. Model 2: for women: adjusted for age, BMI, T2DM, hypertension, hypercholesterolemia, educational levels, smoking status, family history of premature CVD, history of miscarriage, and OCP use; for men: adjusted for age, BMI, T2DM, hypertension, hypercholesterolemia, educational levels, smoking status, and family history of premature CVD