Table 2 Genotype and allele frequencies between study groups
SNP ID | Model | Controls N = 158 (100%) | PE | EOPE | LOPE | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
SNPs | N = 177(%) | ϰ2 | Pa | N = 70(%) | ϰ2 | Pb | N = 107(%) | ϰ2 | PC | ||
rs2232365 | CC | 21(13.29%) | 35(19.77%) | 4.016 | 0.134 | 10(14.29%) | 0.799 | 0.671 | 25(23.36%) | 5.682 | 0.058 |
CT | 80(50.63%) | 93(52.545) | 39(55.71%) | 54(50.47%) | |||||||
TT | 57(36.08%) | 49(27.68%) | 21(30.00%) | 28(26.17%) | |||||||
Genotype | TT+CT/CC | 137(86.71%) | 142(80.23%) | 2.520 | 0.112 | 60(85.71%) | 0.041 | 0.840 | 82(76.63%) | 4.513 | 0.034 |
CC | 21(13.29) | 35(19.77%) | 10(14.29%) | 25(23.36%) | |||||||
Allele | C | 122(38.61%) | 163(47.25%) | 0.052 | 59(42.14%) | 0.477 | 104(48.60%) | 0.021 | |||
T | 194(61.39%) | 191(55.36%) | 81(57.86%) | 110(51.40%) | |||||||
rs3853839 | CC | 10(6.33%) | 15(8.47%) | 3.731 | 0.155 | 7(10.00%) | 0.949 | 0.622 | 8(7.48%) | 6.490 | 0.039 |
CG | 78(49.37%) | 69(38.98%) | 33(47.14%) | 36(33.64%) | |||||||
GG | 70(44.30%) | 93(52.54%) | 30(42.86%) | 63(58.87%) | |||||||
Genotype | CC+CG | 88(55.70%) | 84(47.46%) | 2.268 | 0.132 | 40(57.14%) | 0.041 | 0.839 | 44(41.12%) | 5.412 | 0.020 |
GG | 70(44.30%) | 93(52.54%) | 30(42.86%) | 63(58.88%) | |||||||
Allele | C | 98(31.01%) | 99(28.70%) | 0.747 | 47(33.57%) | 0.293 | 52(24.30%) | 0.092 | |||
G | 218(68.99%) | 255(73.91%) | 93(66.43%) | 162(75.70%) | |||||||
rs3761548 | GG | 88(55.70%) | 87(49.15%) | 1.489 | 0.475 | 33(47.14%) | 1.534 | 0.464 | 54(50.47%) | 0.713 | 0.700 |
GT | 63(39.87%) | 82(46.33%) | 34(48.57%) | 48(44.86%) | |||||||
TT | 7(4.43%) | 8(4.52%) | 3(4.29%) | 5(4.67%) | |||||||
Genotype | TT+TG | 88(55.70%) | 87(49.15%) | 1.433 | 0.231 | 33(47.14%) | 1.425 | 0.233 | 54(50.47%) | 0.701 | 0.401 |
GG | 70(44.30%) | 90(50.85%) | 37(52.86%) | 53(49.53%) | |||||||
Allele | G | 239(75.63%) | 256(74.20%) | 0.329 | 100(71.43%) | 0.343 | 156()72.90% | 0.478 | |||
T | 77(24.37%) | 98(28.41%) | 40(28.57%) | 58(27.11%) | |||||||