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Table 4 Comparation of PPV of Trisomy 21, 18, ONTD and other deformity (n ‰)

From: New cut-off values for screening of trisomy 21, 18 and open neural tube defects (ONTD) during the second trimester in pregnant women with advanced maternal age

Group

n

High risk

Low risk

Sum

Trisomy 21

Trisomy 18

ONTD

Other deformity

Trisomy 21

Trisomy 18

ONTD

Other deformity

Trisomy 21

Trisomy 18

ONTD

Other deformity

Non-AMA

197,101

24(0.12‰)

10(0.05‰)

4(0.02‰)

202(1.02‰)

24(0.12‰)

5(0.03‰)

10(0.05‰)

1445(7.33‰)

48(0.24‰)

15(0.08‰)

14(0.07‰)

1647(8.36‰)

AMA

12,739

20(1.57‰)

1(0.08‰)

0

54(4.24‰)

8(0.63‰)

0

1(0.08‰)

140(10.99‰)

28(2.20‰)

1(0.08‰)

1(0.08‰)

194(15.23‰)

Sum

 

44

11

4

256

32

5

11

1585

76

16

15

1841

  1. AMA advanced maternal age, ONTD Open neural tube defects; Other deformity, chromosomal or structural abnormalities other than Trisomy 21, 18, and ONTD; PPV, positive predictive value