|
Group
|
N
|
AFP (KU/L)
|
AFP (MoM)
|
Free β- hCG (μg/L)
|
|---|
|
Non-AMA
|
197,101
|
37.2(19.20 ~ 75.50)
|
0.98(0.54 ~ 1.87)
|
14.30(4.45 ~ 57.20)
|
|
AMA
|
12,739
|
37.9(19.30 ~ 77.50)
|
1.05(0.56 ~ 1.99)
|
14.30(4.27 ~ 59.75)
|
|
z
| |
6.058
|
21.964
|
1.111
|
|
P
| |
< 0.001
|
< 0.001
|
0.911
|
|
Group
| |
Free β- hCG (MoM)
|
Risk value of Trisomy 21
|
Risk value of Trisomy 18
|
|
Non-AMA
| |
0.99(0.33 ~ 3.60)
|
1/3934(1/133 ~ 1/33336)
|
1/46055(1/2477 ~ 1/100000)
|
|
AMA
| |
1.02(0.33 ~ 3.97)
|
1/1003(1/25 ~ 1/9648)
|
1/11686(1/624 ~ 1/44622)
|
|
z
| |
6.076
|
98.885
|
124.780
|
|
P
| |
< 0.001
|
< 0.001
|
< 0.001
|
- AMA advanced maternal age, AFP alpha-fetoprotein, free β-hCG free beta human chorionic gonadotropin, MoM multiple of the median
