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Table 4 Associations between genotypes of rs2284792 and characteristics among total GDM patients

From: Polymorphisms of TGF-β1 and TGF-β3 in Chinese women with gestational diabetes mellitus

Rs2284792(A/G) AA AG GG AA vs. AG AA vs GG AG vs GG AA vs AG + GG GG vs AG + AA AG vs GG + AA
(n) (n) (n) Pa pb pc pd pe pf
Cases 268 487 164       
Demographic characteristics (Mean ± S)
 Fasting blood glucose (mmol/l) 5.90 ± 2.13 5.75 ± 2.22 5.76 ± 2.33 0.087 0.097 0.960 0.059 0.407 0.360
 Systolic blood pressure (mmHg) 137.65 ± 22.24 137.41 ± 24.86 137.53 ± 22.06 0.166 0.425 0.468 0.224 0.997 0.231
 Diastolic blood pressure (mmHg) 77.09 ± 12.36 77.17 ± 11.86 77.01 0.519 0.560 0.137 0.972 0.186 0.177
 WBC (× 109/L) 10.51 ± 2.99 10.62 ± 3.05 10.62 ± 3.05 0.122 0.144 0.921 0.099 0.514 0.436
 RBC (× 1012/L) 4.41 ± 1.73 4.37 ± 1.17 4.51 ± 1.91 0.588 0.233 0.234 0.997 0.085 0.185
 Hb (g/L) 116.43 ± 17.40 116.47 ± 14.12 116.32 ± 14.31 0.823 0.451 0.308 0.753 0.343 0.560
 neutrophil (×109/L) 8.40 ± 2.54 8.24 ± 2.43 8.44 ± 2.81 0.157 0.779 0.068 0.557 0.167 0.056
 PLT (×109/L) 227.30 ± 58.26 226.72 ± 67.55 226.69 ± 58.86 0.102 0.149 0.953 0.079 0.562 0.252
 PT (s) 10.64 ± 1.59 10.68 ± 1.60 10.71 ± 1.83 0.436 0.283 0.572 0.330 0.402 0.808
 APTT (s) 30.57 ± 3.93 30.52 ± 3.91 30.63 ± 3.38 0.441 0.446 0.134 0.720 0.192 0.300
 ALT (IU/L) 27.66 ± 21.05 26.95 ± 16.47 27.14 ± 19.28 0.065 0.356 0.663 0.075 0.920 0.132
 AST (IU/L) 29.82 ± 18.52 29.53 ± 16.51 29.57 ± 19.35 0.384 0.599 0.930 0.389 0.871 0.510
 Creatinine (umol/L) 58.58 ± 18.75 58.49 ± 19.15 58.49 ± 17.09 0.716 0.788 0.986 0.704 0.931 0.782
 Body mass before pregnancy (kg) 59.73 ± 3.43 63.58 ± 0.95 63.04 ± 0.74 0.146 0.159 0.647 0.116 0.959 0.422
 Body mass increase during pregnancy (kg) 17.53 ± 1.25 17.57 ± 0.62 16.24 ± 0.47 0.978 0.318 0.086 0.614 0.072 0.123
 BMI before pregnancy (kg/m2) 23.97 ± 0.79 24.30 ± 0.34 24.23 ± 0.40 0.698 0.804 0.896 0.754 0.974 0.837
 BMI at birth (kg/m2) 30.7 ± 0.92 30.91 ± 0.42 30.43 ± 0.46 0.841 0.827 0.456 0.964 0.463 0.472
  1. Pa value between AA and AG; Pb value between AA and GG; Pc value between AG and GG; Pd value between AA and AG + GG; Pe value between GG and AG + AA; Pf value between AG and GG + AA
  2. p < 0.05 is considered statistically significant. WBC White Blood Cell, RBC Red Blood Cell, Hb Hemoglobin, PLT Platelet, PT prothrombin time, APTT activated partial thromboplastin time, ALT glutamic pyruvic transaminase, AST glutamic oxaloacetic transaminase