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Table 4 Associations between genotypes of rs2284792 and characteristics among total GDM patients

From: Polymorphisms of TGF-β1 and TGF-β3 in Chinese women with gestational diabetes mellitus

Rs2284792(A/G)

AA

AG

GG

AA vs. AG

AA vs GG

AG vs GG

AA vs AG + GG

GG vs AG + AA

AG vs GG + AA

(n)

(n)

(n)

Pa

pb

pc

pd

pe

pf

Cases

268

487

164

      

Demographic characteristics (Mean ± S)

 Fasting blood glucose (mmol/l)

5.90 ± 2.13

5.75 ± 2.22

5.76 ± 2.33

0.087

0.097

0.960

0.059

0.407

0.360

 Systolic blood pressure (mmHg)

137.65 ± 22.24

137.41 ± 24.86

137.53 ± 22.06

0.166

0.425

0.468

0.224

0.997

0.231

 Diastolic blood pressure (mmHg)

77.09 ± 12.36

77.17 ± 11.86

77.01

0.519

0.560

0.137

0.972

0.186

0.177

 WBC (× 109/L)

10.51 ± 2.99

10.62 ± 3.05

10.62 ± 3.05

0.122

0.144

0.921

0.099

0.514

0.436

 RBC (× 1012/L)

4.41 ± 1.73

4.37 ± 1.17

4.51 ± 1.91

0.588

0.233

0.234

0.997

0.085

0.185

 Hb (g/L)

116.43 ± 17.40

116.47 ± 14.12

116.32 ± 14.31

0.823

0.451

0.308

0.753

0.343

0.560

 neutrophil (×109/L)

8.40 ± 2.54

8.24 ± 2.43

8.44 ± 2.81

0.157

0.779

0.068

0.557

0.167

0.056

 PLT (×109/L)

227.30 ± 58.26

226.72 ± 67.55

226.69 ± 58.86

0.102

0.149

0.953

0.079

0.562

0.252

 PT (s)

10.64 ± 1.59

10.68 ± 1.60

10.71 ± 1.83

0.436

0.283

0.572

0.330

0.402

0.808

 APTT (s)

30.57 ± 3.93

30.52 ± 3.91

30.63 ± 3.38

0.441

0.446

0.134

0.720

0.192

0.300

 ALT (IU/L)

27.66 ± 21.05

26.95 ± 16.47

27.14 ± 19.28

0.065

0.356

0.663

0.075

0.920

0.132

 AST (IU/L)

29.82 ± 18.52

29.53 ± 16.51

29.57 ± 19.35

0.384

0.599

0.930

0.389

0.871

0.510

 Creatinine (umol/L)

58.58 ± 18.75

58.49 ± 19.15

58.49 ± 17.09

0.716

0.788

0.986

0.704

0.931

0.782

 Body mass before pregnancy (kg)

59.73 ± 3.43

63.58 ± 0.95

63.04 ± 0.74

0.146

0.159

0.647

0.116

0.959

0.422

 Body mass increase during pregnancy (kg)

17.53 ± 1.25

17.57 ± 0.62

16.24 ± 0.47

0.978

0.318

0.086

0.614

0.072

0.123

 BMI before pregnancy (kg/m2)

23.97 ± 0.79

24.30 ± 0.34

24.23 ± 0.40

0.698

0.804

0.896

0.754

0.974

0.837

 BMI at birth (kg/m2)

30.7 ± 0.92

30.91 ± 0.42

30.43 ± 0.46

0.841

0.827

0.456

0.964

0.463

0.472

  1. Pa value between AA and AG; Pb value between AA and GG; Pc value between AG and GG; Pd value between AA and AG + GG; Pe value between GG and AG + AA; Pf value between AG and GG + AA
  2. p < 0.05 is considered statistically significant. WBC White Blood Cell, RBC Red Blood Cell, Hb Hemoglobin, PLT Platelet, PT prothrombin time, APTT activated partial thromboplastin time, ALT glutamic pyruvic transaminase, AST glutamic oxaloacetic transaminase