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Table 4 Growth in early pregnancy and risk of preterm birth either spontaneous or medically induced. (N = 2838 births)

From: Accelerated fetal growth in early pregnancy and risk of preterm birth: a prospective cohort study

Growth at second trim scan Spontaneous preterm birth
(n = 1687)
Medically induced preterm birth
(n = 1151)
No. of women Odds ratio (95% CI) No. of women Odds ratio (95% CI)
Crude Adjustedd Crude Adjustedd
Accelerated fetal growtha 234 1.39 (1.21–1.61)* 1.35 (1.15–1.58)* 155 1.37 (1.15–1.63)* 1.34 (1.11–1.63)**
Appropriate fetal growthb 1325 Ref Ref 890 Ref Ref
Delayed fetal growthc 128 0.78 (0.64–0.92)* 0.78 (0.63–0.96)* 106 0.95 (0.77–1.16)*** 0.91 (0.72–1.15)***
  1. aAccelerated fetal growth at second trimester scan was defined as BPD measurement at the 90th percentile, or more of the expected for gestational age
  2. bAppropriate fetal growth at second trimester scan was defined as BPD measurement between 10th - 90th percentile of the expected for gestational age
  3. cDelayed fetal growth at second trimester scan was defined as BPD measurement at the 10th percentile, or less of the expected for gestational age
  4. dAdjusted OR for maternal age older than 35 yrs., short maternal height < 155 cm, BMI ≥ 30 kg/m2, non-Nordic origin, primiparity, smoking, IVF, chronic hypertension, pre-gestational diabetes mellitus and male fetal gender
  5. *p < 0.0001
  6. **p < 0.01
  7. ***p = 0.05