Table 4 Blood parameters in normotensive women with singleton (n = 44) and twin (n = 22) pregnancies

Singleton pregnancies (women tested)

(n = 42)

(n = 42)

(n = 41)

(n = 41)

Twin pregnancies (women tested)

(n = 18)

(n = 21)

(n = 22)

(n = 22)

BNP, pg/mL

SP 8.4 (5.2–11.3)

8.1 (2.9–13.3)

32.0 (15.1–52.6)* †

8.0 (3.6–13.4)

TP 11.0 (5.9–21.4)

20.6 (10.0–29.6) *

56.9 (44.4–74.6) *†

6.1 (2.9–12.2)

NT-proBNP, pg/mL

SP 27 (19–52)

28 (13–49)

110 (44–218) †

30 (18–47)

TP 27 (18–48)

49 (30–113) *

180 (102–228) †

20 (14–48)

hs-TnI, pg/mL

SP 0.9 (0.5–1.3)

1.2 (0.8–1.6)

1.9 (1.1–3.9) †

1.3 (1.0–1.6) †

TP 0.9 (0.2–1.8)

1.5 (1.0–2.2)

1.5 (1.3–4.7) †

0.9 (0.4–1.9)

PRA, ng/mL/h

SP 20 (10–36)

15 (8.4–24)

3.6 (1.9–8.0) †

0.9 (0.5–1.8) †

TP 12 (5.6–20)

11 (5.1–19)

1.9 (0.9–5.9) †

1.3 (0.7–1.5) †

PAC, pg/mL

SP 498 (368–747)

707 (441–1023)

96 (74.4–195) †

116 (77.8–161) †

TP 750 (439–1363)

503 (365–1435)

75 (52–104) *†

102 (58–142) †

Serum creatinine, mg/dL

SP 0.47 (0.41–0.51)

0.49 (0.41–0.56)

0.55 (0.48–0.59) †

0.61 (0.54–0.66)v

TP 0.49 (0.40–0.53)

0.54 (0.49–0.67) *†

0.56 (0.49–0.63) †

0.62 (0.52–0.63) †

eGFR, mL/min/1.73m²

SP 125 (109–138)

118 (99–140)

104 (92–120) †

91 (81–109) †

TP 120 (110–154)

103 (86–118) *†

101 (89–119) †

92 (89–110) †