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Table 4 Multivariable analysis of predictors of mortality

From: Risk factors for mortality among neonates admitted to a special care unit in a low-resource setting

 

p-value

Odds ratio (95% confidence interval)

Year of admission:

0.03

 

 2014

 

Reference

 2015

 

1.00 (0.73 to 1.36)

 2016

 

0.86 (0.63 to 1.16)

 2017

 

0.71 (0.52 to 0.97)

Age at admission, days

0.0003

0.95 (0.93 to 0.97)

Sex:

0.62

 

 Female

 

Reference

 Male

 

1.05 (0.86 to 1.28)

Birth weight:

< 0.0001

 

 Normal weight (≥2500 g)

 

Reference

 Low birth weight (1500–2499 g)

 

2.48 (2.00 to 3.09)

 Very low birth weight (1000–1499 g)

 

11.71 (8.63 to 15.94)

 Extremely low birth weight (< 1000 g)

 

76.04 (28.54 to 263.82)

Birthplace:

< 0.0001

 

 Inborn

 

Reference

 Outborn

 

1.64 (1.31 to 2.06)

Early-onset sepsis:

0.96

 

 No

 

Reference

 Yes

 

0.99 (0.75 to 1.31)

Late-onset sepsis:

0.01

 

 No

 

Reference

 Yes

 

1.63 (1.12 to 2.36)

Intrapartum-related complications:

< 0.0001

 

 No

 

Reference

 Yes

 

4.69 (3.55 to 6.20)

Meconium aspiration syndrome:

0.01

 

 No

 

Reference

 Yes

 

2.34 (1.15 to 4.43)

Respiratory distress:

< 0.0001

 

 No

 

Reference

 Yes

 

2.25 (1.72 to 2.95)

Transient tachypnea of the newborn:

0.26

 

 No

 

Reference

 Yes

 

0.62 (0.25 to 1.33)

Other infections:

0.0007

 

 No

 

Reference

 Yes

 

1.93 (1.31 to 2.81)

Malformations:

0.0002

 

 No

 

Reference

 Yes

 

2.32 (1.49 to 3.57)

  1. In the subsample of 1994 neonates with complete data on temperature at admission and mode of delivery, moderate hypothermia (32–35.9 °C) at admission was a predictor of mortality (OR 1.53, 95% CI 1.09 to 2.15; p = 0.01), while mild hypothermia (36–36.4 °C), hyperthermia (> 37.5 °C) and mode of delivery were not associated with mortality (p = 0.71, p = 0.98 and p = 0.67, respectively)