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Table 4 Laboratory investigations and diagnostics, case note verification, EN-BIRTH study (n = 1015)

From: Antibiotic use for inpatient newborn care with suspected infection: EN-BIRTH multi-country validation study

  Bangladesh Nepal Tanzania All sites pooled (Random Effects)
Azimpur Tertiary Kushtia District Pokhara Regional Temeke Regional Muhimbili National
N = 106 N = 303 N = 344 N = 213 N = 49 N = 1015
n (%) n (%) n (%) n (%) n (%) %
Confirmatory Lab Diagnosis
 Blood Culture Done 2 (1.9) 2 (0.7) 281 (81.7) 1 (0.5) 2 (4.1) 10.6
 Blood Culture Positive 0 (0) 0 (0) 206 (59.9) 0 (0) 1 (2) 5
 LP Done 0 (0) 0 (0) 5 (1.5) 0 (0) 2 (4.1) 0.3
 LP CSF Appearance Positive 0 (0) 0 (0) 1 (0.3) 0 (0) 0 (0) 0
 LP CSF Culture Positive 0 (0) 0 (0) 1 (0.3) 0 (0) 0 (0) 0
 LP CSF Clinical Appearance Positive or Culture Positive 0 (0) 0 (0) 2 (0.58) 0 (0) 1 (2.0) 0.1
 Either Blood Culture Positive OR CSF Positive 0 (0) 0 (0) 207 (60.2) 0 (0) 2 (4.1) 5.5
Other Supportive Lab Diagnosis
 CBC Done 5 (4.7) 9 (3) 309 (89.8) 1 (0.5) 32 (65.3) 25.7
 WBC Count High 1 (0.9) 0 (0) 192 (55.8) 1 (0.5) 15 (30.6) 10.3
 Either Blood Culture Positive or CSF Positive or WBC high 1 (0.9) 0 (0) 277 (80.5) 1 (0.5) 16 (32.7) 14.2
  1. LP lumbar puncture, CSF Cerebrospinal fluid, CBC Complete blood count, WBC White blood cell