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Table 3 Individual-level numerator validation in exit survey report of injectable antibiotics coverage, EN-BIRTH study (n = 901)

From: Antibiotic use for inpatient newborn care with suspected infection: EN-BIRTH multi-country validation study

 

Bangladesh

Nepal

Tanzania

All sites pooled (Random Effects) % and 95 CI

Azimpur Tertiary

Kushtia District

Pokhara Regional

Temeke Regional

Muhimbili National

5.1 Neonatal Infection - Antibiotic/Injection - Survey reported

 Observer coverage %

99.0

(93.4, 99.9)

96.3

(93.4, 97.9)

92.6

(89.3, 95.0)

95.6

(91.8, 97.7)

100.0

(92.5, 100.0)

96.7

(94.0, 98.6)

 Survey reported coverage %

82.5

(73.9, 88.7)

58.1

(52.5, 63.6)

46.8

(41.4, 52.4)

91.1

(85.2, 94.8)

88.6

(72.9, 95.7)

74.7

(55.3, 90.1)

 "Don’t know” responses %

9.7

(5.3, 17.2)

35.2

(30.0, 40.8)

25.0

(20.5, 30.1)

6.8

(3.7, 12.3)

11.4

(4.3, 27.1)

16.9

(7.4, 29.2)

 Sensitivity % (95% CI)

57.8

(51.8, 63.6)

47.8

(41.9, 53.7)

75.9

(55.6, 91.6)

 Specificity % (95% CI)

54.5

(23.4, 83.3)

62.5

(40.6, 81.2)

 Percent agreement (TP+TN)/n %

84.2

(75.6, 90.7)

57.7

(51.8, 63.4)

48.9

(43.2, 54.6)

90.8

(84.9, 95.0)

88.6

(73.3, 96.8)

75.3

(56.4, 90.2)

5.2 Neonatal Infection - Antibiotic name - Survey reported

 Observer coverage %

99.0

(93.4, 99.9)

96.3

(93.4, 97.9)

92.6

(89.3, 95.0)

95.6

(91.8, 97.7)

100.0

(92.5, 100.0)

96.7

(94.0, 98.6)

 Survey reported coverage %

4.9

(2.0, 11.2)

25.2

(20.6, 30.5)

3.2

(1.7, 5.8)

21.2

(15.3, 28.7)

14.3

(6.0, 30.4)

12.3

(3.5, 25.1)

 "Don’t know” responses %

9.7

(5.3, 17.2)

35.2

(30.0, 40.8)

25.0

(20.5, 30.1)

6.8

(3.7, 12.3)

11.4

(4.3, 27.1)

16.9

(7.4, 29.2)

 Sensitivity % (95% CI)

26.2

(21.2, 31.8)

3.5

(1.7, 6.3)

12.7

(3.7, 25.6)

 Specificity % (95% CI)

90.9

(58.7, 99.8)

100.0

(85.8, 100.0)

 Percent agreement (TP+TN)/n %

5.9

(2.2, 12.5)

28.7

(23.6, 34.2)

10.9

(7.6, 14.8)

23.9

(17.2, 31.8)

14.3

(4.8, 30.3)

16.1

(8.0, 26.2)

  1. †‡ Validity statistics suppressed where < 10 count in either column of two-by-two table