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Table 3 Summary of findings among studies comparing immediate induction with delayed induction of labour

From: Immediate versus delayed induction of labour in hypertensive disorders of pregnancy: a systematic review and meta-analysis

Outcome

Number of studies pooled

Events

Immediate Induction of labour

Total Immediate Induction of labour

Events Delayed induction

Total

Delayed induction

Pooled RR (95% CI)

I2

Reference

Figure

Early onset severe pre-eclampsia

 Maternal mortality

3

0

630

1

636

0.34 (0.01–8.23)

NA

[24, 25, 31]

Additional file 2: Appendix 1.1

 Eclampsia

2

1

179

1

180

0.98 (0.06–15.58)

NA

[31, 33]

Additional file 2: Appendix 1.4

 Severe renal impairment

3

1

199

4

198

0.32 (0.05–1.99)

0%

[31,32,33]

Additional file 2: Appendix 1.6

 HELLP syndrome

4

7

872

18

856

0.40 (0.17–0.94)

0%

[22, 23, 27, 28]

Additional file 2: Appendix 1.7

 Caesarean section

6

463

710

500

718

0.95 (0.89–1.01)

10%

[24, 25, 30,31,32,33]

Additional file 2: Appendix 1.13

 Placental abruption

4

7

225

17

228

0.47 (0.20–1.12)

0%

[25, 31,32,33]

Additional file 2: Appendix 1.14

 Stillbirths

5

1

689

2

695

0.60 (0.07–4.73)

0%

[24, 30,31,32,33]

Additional file 2: Appendix 1.16

 Perinatal mortality

5

21

672

19

677

1.14 (0.64–2.02)

0%

[24, 25, 30,31,32]

Additional file 2: Appendix 1.19

 Neonatal mortality

5

10

581

6

588

1.60 (0.66–3.88)

0%

[24, 25, 30,31,32]

Additional file 2: Appendix 1.22

 Respiratory distress syndrome

3

81

537

56

542

1.69 (1.00–2.85)

55%

[24, 32, 33]

Additional file 2: Appendix 1.24

 Small for gestational age babies

4

94

669

149

677

0.49 (0.29–0.84)

60%

[24, 30, 31, 33]

Additional file 2: Appendix 1.29

 Neonatal intensive care unit admission

4

183

669

168

667

1.22 (0.95–1.56)

75%

[24, 30, 31, 33]

Additional file 2: Appendix 1.32

 Intraventricular haemorrhage

1

4

137

1

138

4.03 (0.46–35.59)

NA

[33]

 Necrotizing enterocolitis

3

9

203

3

205

2.23 (0.42–11.87)

29%

[31,32,33]

Additional file 2: Appendix 1.33

Late onset mild pre-eclampsia

 Maternal mortality

4

1

1099

0

1110

3.07 (0.13–75.19)

NA

[15, 22, 23, 27]

Additional file 2: Appendix 1.2

 Eclampsia

4

1

1099

2

1110

0.76 (0.05–11.18)

34%

[15, 22, 23, 27]

Additional file 2: Appendix 1.3

 Severe renal impairment

2

5

99

14

101

0.36 (0.14–0.92)

NA

[22, 29]

Additional file 2: Appendix 1.5

 HELLP syndrome

2

22

179

19

180

1.15 (0.65–2.02)

0%

[31, 33]

Additional file 2: Appendix 1.8

 Thromboembolic disease

3

2

1050

1

1059

1.60 (0.20–12.99)

0%

[15, 23, 27]

Additional file 2: Appendix 1.9

 Postpartum haemorrhage

3

46

740

57

751

0.82 (0.56–1.19)

0%

[15, 22, 27]

Additional file 2: Appendix 1.10

 Caesarean section

6

276

1243

288

1235

0.95 (0.82–1.09)

0%

[15, 22, 23, 27,28,29]

Additional file 2: Appendix 1.11

 Stillbirths

3

1

814

5

801

0.17 (0.02–1.45)

NA

[15, 23, 26]

Additional file 2: Appendix 1.15

 Perinatal mortality

4

1

1099

0

1110

3.12 (0.13–74.80)

NA

[15, 22, 23, 27]

Additional file 2: Appendix 1.18

 Neonatal mortality

4

1

1099

0

1110

3.12 (0.13–74.80)

NA

[15, 22, 23, 27]

Additional file 2: Appendix 1.21

 Respiratory distress syndrome

3

32

771

13

740

2.15 (1.14–4.06)

0%

[23, 27, 28]

Additional file 2: 1.23

 Neonatal seizures

1

4

351

1

348

3.97 (0.45–35.30)

NA

[23]

Additional file 2: Appendix 1.26

 Small for gestational age babies

4

240

841

256

834

1.19 (0.73–1.94)

45%

[15, 22, 27, 28]

Additional file 2: Appendix 1.27

 Neonatal intensive care unit admission

5

68

1140

49

1119

1.28 (0.87–1.87)

10%

[15, 22, 23, 27, 28]

Additional file 2: Appendix 1.30

Early onset mild pre-eclampsia

 Caesarean

2

152

179

113

159

1.49 (0.68–3.23)

73%

[16, 26]

Additional file 2: Appendix 1.12

 Perinatal mortality

2

27

334

22

329

1.20 (0.70–2.07)

0%

[16, 26]

Additional file 2: Appendix 1.17

 Neonatal mortality

2

23

179

16

159

1.24 (0.68–2.25)

0%

[16, 26]

Additional file 2: Appendix 1.20

 Neonatal seizures

1

3

141

1

121

2.57 (0.27–24.43)

NA

[16]

Additional file 2: Appendix 1.25

 Small for gestational age babies

1

6

38

4

38

1.50 (0.46–4.89)

NA

[16]

Additional file 2: Appendix 1.28

 Neonatal intensive care unit admission

1

12

38

3

38

4.00 (1.23–13.05)

NA

[16]

Additional file 2: Appendix 1.31

 Intraventricular haemorrhage

1

34

141

16

121

1.82 (1.06–3.14)

NA

[26]

  1. NA Not applicable