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Table 2 Median (minimum-maximum) intrafollicular cytokine concentrations, LLOQ, ULOQ (pg/ml) of normoresponders, and moderate-to-severe OHSS groups of the study

From: Prognostic role of follicular fluid tumor necrosis factor alpha in the risk of early ovarian hyperstimulation syndrome

Cytokine (pg/ml) Normoresponders
n = 19
Low-risk OHSS
n = 13
High-risk OHSS
n = 28
LLOQ
(pg/ml)
ULOQ
(pg/ml)
GM-CSF 12 (10–13) 11.5 (10–12.5) 11.5 (10–60) 11.9 2881.1
IL-1β 13 (11.5–14) 13 (12–13.8) 13 (12–15.3) 16.2 3961
IL-6 34 (18.5–186.3) 34 (22–435.5) 28 (18–461) 4.5 1103.3
IL-2 33 (16.5–37.8) 30 (23.5–37.5) 31.15 (22.8–36) 28.8 7439.4
IFN-γ 18 (16.8–19.5) 18 (16–18.8) 17.5 (15.5–22) 49.2 11,949.1
TNF-α 12 (11–13) 12 (10.5–13) 11 (10.5–12.5)* 8.9 2161.5
CXCL8/IL-8 760.8 (309–1863.8) 697.8 (206.3–1796.8) 650.3 (207–1339.5) 4.4 1060.6
IL-10 43.8 (34.8–60) 38.0 (33.5–69.0) 47.65 (32.5–67.5) 7.3 882.9
IL-4 16 (13.8–17.8) 15.8 (14.5–17.5) 15.5 (14–17.3) 15.4 3750
IL-5 10.5 (9.5–11.5) 10.0 (9–11) 10.15 (9–12) 6.3 1539.2
  1. * Differences were statistically significant (p <0.05). Values are presented as median (minimum- maximum) in the three groups of the study; LLOQ Lower limit of qualification, ULOQ Upper limit of qualification, GM- CSF Granulocyte macrophage-colony stimulating factor, IL interleukin, INF-γ interferon gamma, TNF-α tumor necrosis factor-alpha