Table 2 Median (minimum-maximum) intrafollicular cytokine concentrations, LLOQ, ULOQ (pg/ml) of normoresponders, and moderate-to-severe OHSS groups of the study
Cytokine (pg/ml) | Normoresponders n = 19 | Low-risk OHSS n = 13 | High-risk OHSS n = 28 | LLOQ (pg/ml) | ULOQ (pg/ml) |
|---|---|---|---|---|---|
GM-CSF | 12 (10–13) | 11.5 (10–12.5) | 11.5 (10–60) | 11.9 | 2881.1 |
IL-1β | 13 (11.5–14) | 13 (12–13.8) | 13 (12–15.3) | 16.2 | 3961 |
IL-6 | 34 (18.5–186.3) | 34 (22–435.5) | 28 (18–461) | 4.5 | 1103.3 |
IL-2 | 33 (16.5–37.8) | 30 (23.5–37.5) | 31.15 (22.8–36) | 28.8 | 7439.4 |
IFN-γ | 18 (16.8–19.5) | 18 (16–18.8) | 17.5 (15.5–22) | 49.2 | 11,949.1 |
TNF-α | 12 (11–13) | 12 (10.5–13) | 11 (10.5–12.5)* | 8.9 | 2161.5 |
CXCL8/IL-8 | 760.8 (309–1863.8) | 697.8 (206.3–1796.8) | 650.3 (207–1339.5) | 4.4 | 1060.6 |
IL-10 | 43.8 (34.8–60) | 38.0 (33.5–69.0) | 47.65 (32.5–67.5) | 7.3 | 882.9 |
IL-4 | 16 (13.8–17.8) | 15.8 (14.5–17.5) | 15.5 (14–17.3) | 15.4 | 3750 |
IL-5 | 10.5 (9.5–11.5) | 10.0 (9–11) | 10.15 (9–12) | 6.3 | 1539.2 |