|
M0
|
Recruitment (preconception or 1st trimester)
|
Informed consent
|
Participant
|
Family health centers
|
|
Sociodemographic evaluation
|
Participant
|
|
Clinical evaluation
|
Clinician
|
|
Food frequency questionnaire
|
Participant
|
|
3 days food record
|
Participant
|
Home
|
|
Blood and urine collection
|
Clinical Analysis Laboratory
|
|
Thyroid ultrasound
|
Clinician
|
2CA
|
|
M1
|
1st trimester of pregnancy
|
Clinical evaluation
|
Clinician
|
Family health centers
|
|
Blood and urine collection
|
Clinical Analysis Laboratory
|
|
M2
|
2nd trimester of pregnancy
|
Clinical evaluation
|
Clinician
|
Family health centers
|
|
Blood and urine collection
|
Clinical Analysis Laboratory
|
|
M3
|
3rd trimester of pregnancy
|
Clinical evaluation
|
Clinician
|
Family health centers
|
|
Blood and urine collection
|
Clinical Analysis Laboratory
|
|
Thyroid ultrasound
|
Clinician
|
2CA
|
|
Fetal cardiotocography
|
Clinician/Nurse
|
Hospital Braga
|
|
M4
|
Birth
|
Clinical evaluation
|
Clinician
|
Hospital Braga
|
|
Blood and urine collection - pregnant
|
Nurse
|
|
Urine collection– Newborn
|
|
M5
|
3 months after birth
|
Breast milk collection
|
Nurse
|
2CA
|
|
Blood and urine collection – puerperal women
|
|
Urine collection – newborn
|
|
Thyroid ultrasound - puerperal women
|
Clinician
|
|
Thyroid ultrasound - child
|
|
M6
|
18 months after birth
|
Child psychomotor evaluation
|
Researcher
|
2CA
|
|
Blood and urine collection –women
|
Nurse
|
|
Urine collection – child
|
