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Table 1 Baseline demographic and clinical characteristics

From: Longitudinal change in arterial stiffness after delivery in women with preeclampsia and normotension: a prospective cohort study

Variable

Preeclampsia (n = 37)

Control (n = 36)

P valuea

Age, years

34.8 ± 3.6

32.9 ± 3.6

0.029

History of preeclampsia, n (%)

2 (5.4)

1 (2.8)

0.999

Onset of preeclampsia, n (%)

 Early onset

22 (59.5)

  

 Late onset

15 (40.5)

  

Peak body weight during pregnancy, kg

70.4 ± 11.8

65.6 ± 7.5

0.042 (0.108b)

Primipara

24 (64.9)

24 (66.7)

0.871

Twins, n (%)

4 (10.8)

1 (2.8)

0.358

Gestational week at delivery

33.7 ± 3.0

37.7 ± 2.0

<0.001

Fetal birth weight, kg

1.79 ± 0.58

2.93 ± 0.52

<0.001

Waist-to-hip ratio

0.92 ± 0.05

0.92 ± 0.06

0.874

BMI, m2/kg

27.4 ± 5.0

25.0 ± 2.8

0.015 (0.050b)

Mean CAVIc

6.92 ± 1.69

6.53 ± 1.50

0.306 (0.032b)

Hypertensiond, n (%)

2 (5.4)

0

0.494

Diabetes mellituse, n (%)

4 (10.8)

0

0.115

SBP, mmHg

142.4 ± 12.7

111.4 ± 10.5

< 0.001

DBP, mmHg

83.9 ± 9.3

63.2 ± 7.8

< 0.001

Hemoglobin, mg/dL

12.0 ± 2.0

11.4 ± 1.8

0.164

Total cholesterol, mg/dL

232.6 ± 49.6

208.6 ± 46.3

0.036

HDL cholesterol, mg/dL

59.9 ± 14.6

62.6 ± 13.1

0.419

LDL cholesterol, mg/dL

126.2 ± 33.0

112.2 ± 33.7

0.082 (0.017b)

Triglyceride, mg/dL

255.6 ± 92.5

213.6 ± 60.5

0.026 (0.061b)

Creatinine, mg/dL

0.693 ± 0.255

0.532 ± 0.092

0.001 (0.007b)

AST, IU/L

31.0 ± 17.2

17.9 ± 7.6

< 0.001

ALT, IU/L

27.0 ± 26.9

11.4 ± 6.2

0.002 (<0.001b)

Hypertension treatment, n (%)

23 (62.2%)

0%

<0.001

Treatment regimen, n (%)

 Single drug

13 (56.5)

  

 Two drugs

8 (34.8)

  

 Three drugs

2 (8.7)

  

Type of antihypertensive drug, n (%)

 CCB

23 (100%)

  

 BB

2 (8.7%)

  
  1. Data are presented as numbers and percentages or mean ± SD. aT-test or Chi-square test. bThe Mann-Whitney test was used due to a skewed distribution. cThe mean CAVI is the average of the right and left CAVIs. drefers to pre-pregnancy hypertension. eTwo women had type-1 diabetes mellitus; the remaining women had type-2 diabetes mellitus
  2. SD Standard deviation, BMI Body mass index, CAVI Cardio-ankle vascular index, SBP Systolic blood pressure, DBP Diastolic blood pressure, HDL High density lipoprotein, LDL Low density lipoprotein, AST Aspartate aminotransferase, ALT Alanine aminotransferase, CCB Calcium channel blocker, BB Beta blocker