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Table 2 Neonatal outcomes in women who underwent pre-labor cesarean section (PrlCS) or induction of labor (IOL)

From: Cesarean delivery or induction of labor in pre-labor twin gestations: a secondary analysis of the twin birth study

Outcome n (%) PrlCS (n = 938) IOL (n = 409) aOR (95% CI) P
Composite primary outcome 31 (1.7) 16 (2.0) 0.8 (0.4–1.6) 0.61
Death 15 (0.8) 6 (0.7) 1.1 (0.4–3.3) 0.88
Serious neonatal morbiditya 16 (0.9) 10 (1.2) 0.7 (0.3–1.6) 0.4
Birth trauma b 2 (0.1) 2 (0.2) 0.4 (0.0–4.8) 0.49
Apgar score < 4 at 5 min 2 (0.1) 3 (0.4) 0.28 (0.0–1.7) 0.24
Abnormal level of consciousness c 0 0  
≥2 Seizures within 72 h after birth 0 2 (0.3)   0.09
Assisted ventilation d 12 (0.7) 2 (0.3) 2.61 (0.6–11.9) 0.13
Neonatal sepsis within 72 h after birth 0 0  
Necrotizing enterocolitis 0 1 (0.1)   0.30
Cystic periventricular leukomalacia 2 (0.1) 0   0.99
  1. PrlCS Pre-labor cesarean section, IOL Induction of labor
  2. Adjusted odds ratio (aOR) and their 95% confidence intervals (95%-CI) represent the result of a generalized estimating equation, accounting for maternal age, parity, previous CS, gestational age at delivery, presentation at delivery, antenatal corticosteroids use and for the correlation between infants from the same pregnancy
  3. aSerious neonatal morbidity: bbirth trauma (long-bone fracture, other bone fracture, facial-nerve injury at 72 h of age or at discharge, intracerebral hemorrhage); Apgar score < 4 at 5 min; neurological (≥ 2 seizures before 72 h of age; coma; stupor or decreased response to pain); respiratory (assisted ventilation for ≥24 h by endotracheal tube, inserted before 72 h of age; bronchopulmonary dysplasia); neonatal sepsis before 72 h of age; necrotizing enterocolitis; grade III or IV intraventricular hemorrhage and cystic periventricular leukomalacia
  4. cAbnormal level of consciousness: Coma, stupor or decreased response to pain, hyperalert, drowsy, or lethargic
  5. dAssisted ventilation for ≥24 h by means of endotracheal tube, inserted within 72 h after birth