From: Application of chromosome microarray analysis in prenatal diagnosis
Prenatal diagnostic indications | n | Abnormal karyotype | Detection rate (%) | PCNVS | Detection rate (%) | VOUS | Detection rate (%) |
---|---|---|---|---|---|---|---|
NIPT abnormal | 25 | 8 | 32 | 1 | 4 | 4 | 16 |
Advanced maternal age | 3 | 2 | 66.6 | Ā | Ā | Ā | Ā |
Abnormal karyotypeof couple | 8 | 1 | 12.5 | 0 | Ā | 1 | 12.5 |
Fetal Karyotype | 11 | 1 | 9.09 | 1 | 9.09 | 1 | 9.09 |
High-risk screening | 3 | 0 | 0 | 1 | 33.33 | 1 | 33 |
Stillbirth | 9 | Ā | Ā | Ā | Ā | 2 | 22.2 |
Historyof adverse pregnancy | 3 | Ā | Ā | Ā | Ā | 1 | 33 |
FISH does not match karyotype | 2 | Ā | Ā | Ā | Ā | 1 | 50 |
Total | 64 | 12 | 18.75 | 3 | 4.68 | 11 | 17.19 |