From: Application of chromosome microarray analysis in prenatal diagnosis
Prenatal diagnostic indications | n | Abnormal karyotype | Detection rate(%) | PCNVS | Detection rate (%) | VOUS | Detection rate (%) |
---|---|---|---|---|---|---|---|
Single malformation | Ā | Ā | Ā | Ā | Ā | Ā | Ā |
Heart malformation | 63 | 3 | 4.76 | 2 | 3.17 | 5 | 7.94 |
Urinary system abnormalities | 56 | 0 | Ā | 3 | 5.35 | 1 | 1.78 |
Nervous system abnormalities | 15 | 0 | Ā | 2 | 13.3 | 5 | 33.33 |
Digestive disorders | 22 | 0 | Ā | 1 | 4.55 | 2 | 9.09 |
Hydrocyst of the neck | 8 | 1 | 12.5 | 0 | Ā | Ā | Ā |
Foot inversion | 4 | 1 | 25 | 0 | Ā | Ā | Ā |
Cleft lip and palate | 5 | 0 | Ā | 2 | 40 | Ā | Ā |
Skeletal abnormalities | 11 | 0 | Ā | 0 | Ā | Ā | Ā |
Respiratory system | 10 | Ā | Ā | Ā | Ā | Ā | Ā |
Pleural effusion | 7 | Ā | Ā | Ā | Ā | Ā | Ā |
Total | 201 | 5 | 2.49 | 10 | 4.97 | 13 | 6.47 |
Multiple malformations | 9 | 3 | 33.33 | 0 | Ā | Ā | Ā |
Total | 210 | 8 | 3.81 | 10 | 4.76 | 13 | 6.19 |