Skip to main content

Table 3 The neonatal outcomes of patients among groups A–E stratified by 35 years of age

From: Live birth rate and neonatal outcomes of different quantities and qualities of frozen transferred blastocyst in patients requiring whole embryo freezing stratified by age

 

<35 years of age

≥ 35 years of age

Group A

Group B

Group C

Group D

Group E

P

Group A

Group B

Group C

Group D

Group E

P

Cycles (n)

1425

844

206

183

120

 

144

269

107

39

25

 

Preterm birth

(<37weeks)

11.77a,b,c

(91/773)

39.45

(215/545)

33.33

(44/132)

42.70

(38/89)

4.55d

(2/44)

0.000

8.20a,b

(5/61)

35.0

(56/160)

25.0

(13/52)

16.67

(2/12)

16.67

(1/6)

0.001

Singleton

8.67a

(67/773)

3.30

(18/545)

6.82

(9/132)

3.37

(3/89)

4.55

(2/44)

0.001

4.92

(3/61)

5.62

(9/160)

7.69

(4/52)

0.0

(0/12)

0.0

(0/6)

0.755

Twin

3.10a,b,c

(24/773)

36.15

(197/545)

26.51

(35/132)

39.33

(35/89)

0.0d

(0/44)

0.000

3.28a,b

(2/61)

29.38

(47/160)

17.31

(9/52)

16.67

(2/12)

16.67

(1/6)

0.000

Gestational age (weeks)

38.70 ± 1.94a,b,c

37.37 ± 2.52

37.59 ± 2.52

36.86 ± 3.33

39.18 ± 1.91d

0.000

38.72 ± 1.23a,b,c

37.61 ± 2.33

37.66 ± 2.89

37.00 ± 3.43

38.32 ± 0.86d

0.022

Singleton

38.80 ± 1.83

38.94 ± 1.71

38.51 ± 2.18

39.00 ± 1.58

39.18 ± 1.91

0.325

38.81 ± 1.56

38.59 ± 2.14

38.76 ± 1.97

38.52 ± 1.71

38.32 ± 0.86

0.951

Twin

35.32 ± 1.47

36.04 ± 2.32

36.02 ± 2.37

35.15 ± 3.01

/

0.095#

36.20 ± 0.40

35.98 ± 1.63

35.06 ± 3.21

34.29 ± 4.99

/

0.330#

Birth height (mm)

49.51 ± 2.3a,b,c

47.72 ± 3.21

48.23 ± 2.41

46.61 ± 4.26

49.89 ± 2.22d

0.000

49.77 ± 1.85a,b,c

48.03 ± 2.70

47.95 ± 3.75

48.31 ± 5.70

49.75 ± 0.96d

0.000

Singleton

49.68 ± 2.27

49.82 ± 1.98

49.88 ± 1.73

49.53 ± 1.44

49.88 ± 2.22

0.838

49.93 ± 1.76

49.50 ± 2.39

49.77 ± 2.41

50.00 ± 2.00

49.75 ± 0.96

0.868

Twin

46.66 ± 2.40

46.72 ± 2.95

46.97 ± 2.20

45.50 ± 4.32

/

0.113#

46.75 ± 0.35

46.90 ± 1.91

45.70 ± 3.70

45.83 ± 6.83

/

0.155#

Birth weight (kg)

3.16 ± .054a,b,c

2.73 ± 0.61

2.79 ± 0.62

2.57 ± 0.66

3.19 ± 0.43d

0.000

3.12 ± 0.51a,b,c

2.76 ± 0.60

2.81 ± 0.75

2.55 ± 0.88

3.30 ± 0.29d

0.000

Singleton

3.22 ± 0.50

3.27 ± 0.51

3.24 ± 0.52

3.17 ± 0.33

3.19 ± 0.43

0.583

3.36 ± 0.49

3.22 ± 0.50

3.24 ± 0.49

3.26 ± 0.45

3.30 ± 0.29

0.666

Twin

2.34 ± 0.43

2.48 ± 0.45

2.44 ± 0.42

2.31 ± 0.54

/

0.113#

2.55 ± 0.25

2.43 ± 0.34

2.24 ± 0.52

2.00 ± 0.82

/

0.142#

Still birth

0.0

(0/773)

0.0

(0/545)

0.0

(0/132)

0.0

(0/89)

0.0

(0/44)

/

0.0

(0/61)

0.0

(0/160)

0.0

(0/52)

0.0

(0/12)

0.0

(0/6)

/

Congenital anomalies

1.64

(13/795)

1.60

(13/811)

1.09

(2/184)

1.52

(2/132)

2.27

(1/44)

0.958

0.0

(0/63)

0.0

(0/217)

0.0

(0/68)

0.0

(0/15)

0.0

(0/6)

/

Sex ratio(male/female)

1.30

(450/345)

1.43

(477/334)

1.10

(97/87)

1.46

(78/54)

0.83

(20/24)

0.445

1.43

(37/26)

1.22

(119/98)

1.16

(37/31)

0.63

(6/9)

1.00

(3/3)

0.632

Low birth weight

(<2500 g) in singleton

7.04a,b,c

(56/795)

27.25

(221/811)

28.26

(52/184)

34.09

(45/132)

4.55d

(2/44)

0.000

6.34a,b

(4/63)

29.03

(63/217)

27.94

(19/68)

13.33

(2/15)

0.0

(0/6)

0.002

Singleton

4.02

(32/795)

4.44

(36/811)

4.35

(8/184)

4.55

(6/132)

4.55

(2/44)

0.977

3.17

(2/63)

2.76

(6/217)

1.47

(1/68)

0.0

(0/1)

0.0

(0/6)

0.833

Twin

3.02a,b,c

(24/795)

22.81

(185/811)

23.91

(44/184)

29.54

(39/132)

0.0d

(0/44)

0.000

3.17a,b

(2/63)

26.27

(57/217)

26.47

(18/68)

13.33

(2/15)

0.0

(0/6)

0.001

Very low birth weight (<1500 g) in singleton

0.75a,c

(6/795)

2.84

(23/811)

1.63

(3/184)

5.30

(7/132)

0.0

(0/44)

0.001

0.0c

(0/63)

2.76

(6/217)

2.94

(2/68)

13.33

(2/15)

0.0

(0/6)

0.045

Singleton

0.63

(5/795)

0.12

(1/811)

0.54

(1/184)

0.0

(0/132)

0.0

(0/44)

0.324

0.0

(0/63)

0.5

(1/217)

0.0

(0/68)

0.0

(0/15)

0.0

(0/6)

0.879

Twin

0.12a,c

(1/795)

2.72

(22/811)

1.09

(2/184)

5.30

(7/13)

0.0

(0/44)

0.000

0.0c

(0/63)

2.30

(5/217)

2.94

(2/68)

13.33

(2/15)

0.0

(0/6)

0.029

  1. #comparison among groups A–D. P < .05 was considered statistically significant
  2. aP < .05 compared to group B
  3. bP < .05 compared to group C
  4. cP < .05 compared to group D
  5. dP < .05 between groups D and E