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Table 4 Reclassification Table for Extended Model with PlGF (fullPIERS plus PlGF)

From: Placental growth factor for the prognosis of women with preeclampsia (fullPIERS model extension): context matters

fullPIERS Model without PlGF
Predicted probability Women with events Women without events Total
0 to 9% 37 475 512
≥ 10% 7 22 29
Total 44 497 541
fullPIERS model with PlGF
Predicted probability Women with events Women without events Total
0 to 9% 29 416 445
≥ 10% 15 81 96
Total 44 497 541
  1. Net reclassification index (NRI) calculation
  2. Original fullPIERS model
  3. Sensitivity = 37/44*100 = 84.1%; Specificity = 22/497*100 = 4.4%
  4. fullPIERS model + PlGF (extended fullPIERS model)
  5. Sensitivity = 29/44*100 = 65.9%; Specificity =81/497*100 = 16.3%
  6. Improved sensitivity = 65.9–84.3% = −18.4%; Improved specificity = 16.3–4.4% = 11.9%
  7. NRI = Improved sensitivity + Improved specificity = − 18.4% + 9.7% = −8.7%