|
fullPIERS Model without PlGF
|
|---|
|
Predicted probability
|
Women with events
|
Women without events
|
Total
|
|---|
|
0 to 9%
|
37
|
475
|
512
|
|
≥ 10%
|
7
|
22
|
29
|
|
Total
|
44
|
497
|
541
|
|
fullPIERS model with PlGF
|
|
Predicted probability
|
Women with events
|
Women without events
|
Total
|
|
0 to 9%
|
29
|
416
|
445
|
|
≥ 10%
|
15
|
81
|
96
|
|
Total
|
44
|
497
|
541
|
- Net reclassification index (NRI) calculation
- Original fullPIERS model
- Sensitivity = 37/44*100 = 84.1%; Specificity = 22/497*100 = 4.4%
- fullPIERS model + PlGF (extended fullPIERS model)
- Sensitivity = 29/44*100 = 65.9%; Specificity =81/497*100 = 16.3%
- Improved sensitivity = 65.9–84.3% = −18.4%; Improved specificity = 16.3–4.4% = 11.9%
- NRI = Improved sensitivity + Improved specificity = − 18.4% + 9.7% = −8.7%
