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Table 2 Maternal characteristics for the fullPIERS Development cohort vs Extension cohort, (n (%) or median (interquartile range))

From: Placental growth factor for the prognosis of women with preeclampsia (fullPIERS model extension): context matters

Characteristics

fullPIERS cohort (development)

(2023 women)

Extension cohort

(541 women)

P value

DEMOGRAPHICS & PREGNANCY CHARACTERISTICS

 Maternal age at EDD (year)

31 [27, 36]

30 [24, 34]

< 0.001

 Parity ≥ 1

581 (28·7%)

219 (40.4%)

< 0.001

 Gestational age at eligibility (week)

36 [33, 38·3]

33.0 [29.7, 35.9]

< 0.001

 Gestational age at eligibility < 34 weeks, N

636 (31.4%)

307 (56.7%)

< 0.001

 Multiple pregnancy

192 (9·5%)

43 (8.0%)

0.2468

 Smoking in this pregnancy

249 (12·3%)

118 (21.8%)

< 0.001

INTERVENTIONS DURING ADMISSION

 Corticosteroids, GA onset < 34

440/636 (69.2%)

128/307 (41.7%)

< 0.001

 Antihypertensive therapy

1381 (68·3%)

384 (71.0%)

0.054

 MgSO4

690 (34·1%)

410 (75.8%)

< 0.001

PREGNANCY OUTCOMES

 Admission-To-Delivery Interval, < 34+ 0 Weeks (Days), mean (SD)

10.9 (11)

5.0 (8)

< 0.001

 Gestational age at delivery (week), median (IQR)

36.9 [34·1, 38·6]

33.9 [30.5, 36.4]

< 0.001

 Stillbirth

20 (1.0%)

10 (1.9%)

0.2489

 Neonatal death

26 (1·3%)

12 (2.2%)

0.0989

ADVERSE MATERNAL OUTCOME (N women)

 Within 48 h

106 (5.2%)

44 (8.1%)

0.023

 Within 7 days

203 (10.0%)

52 (9.6%)

0.067

 At anytime

261 (12.9%)

57 (10.5%)

0.243

  1. Abbreviations: EDD – Estimated date of delivery, GA – Gestational age, MgSO4 – Magnesium sulphate, SD – standard deviation, IQR – interquartile range