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Table 2 Maternal characteristics for the fullPIERS Development cohort vs Extension cohort, (n (%) or median (interquartile range))

From: Placental growth factor for the prognosis of women with preeclampsia (fullPIERS model extension): context matters

Characteristics fullPIERS cohort (development)
(2023 women)
Extension cohort
(541 women)
P value
DEMOGRAPHICS & PREGNANCY CHARACTERISTICS
Maternal age at EDD (year) 31 [27, 36] 30 [24, 34] < 0.001
Parity ≥ 1 581 (28·7%) 219 (40.4%) < 0.001
Gestational age at eligibility (week) 36 [33, 38·3] 33.0 [29.7, 35.9] < 0.001
Gestational age at eligibility < 34 weeks, N 636 (31.4%) 307 (56.7%) < 0.001
Multiple pregnancy 192 (9·5%) 43 (8.0%) 0.2468
Smoking in this pregnancy 249 (12·3%) 118 (21.8%) < 0.001
INTERVENTIONS DURING ADMISSION
Corticosteroids, GA onset < 34 440/636 (69.2%) 128/307 (41.7%) < 0.001
Antihypertensive therapy 1381 (68·3%) 384 (71.0%) 0.054
MgSO4 690 (34·1%) 410 (75.8%) < 0.001
PREGNANCY OUTCOMES
Admission-To-Delivery Interval, < 34+ 0 Weeks (Days), mean (SD) 10.9 (11) 5.0 (8) < 0.001
Gestational age at delivery (week), median (IQR) 36.9 [34·1, 38·6] 33.9 [30.5, 36.4] < 0.001
Stillbirth 20 (1.0%) 10 (1.9%) 0.2489
Neonatal death 26 (1·3%) 12 (2.2%) 0.0989
ADVERSE MATERNAL OUTCOME (N women)
Within 48 h 106 (5.2%) 44 (8.1%) 0.023
Within 7 days 203 (10.0%) 52 (9.6%) 0.067
At anytime 261 (12.9%) 57 (10.5%) 0.243
  1. Abbreviations: EDD – Estimated date of delivery, GA – Gestational age, MgSO4 – Magnesium sulphate, SD – standard deviation, IQR – interquartile range