Distribution of maternal red cell antibodies and the risk of severe alloimmune haemolytic disease of the foetus in a Chinese population: a cohort study on prenatal management

Table 4 Characteristics of anaemic foetuses in the three groups

	Anti-D n = 79	Anti-D combined with others n = 22	P	Other single-antibody n = 11	P
Previously affected pregnancies per women	1(0–1)	2(1–2)	0.002 ^*	1(0–1)	0.990
Maternal antibody titre	1:512 (1:512-1:2048)	1:768 (1:256-1:2560)	0.561	1:32 (1:8 − 1:256)	<0.001 ^*
Haemoglobin (g/L)^a	68.4 ± 26.6	67.7 ± 23.6	0.908	50.2 ± 23.1	0.033 ^*
Haematocrit (%)^a	20.9 ± 7.7	20.5 ± 6.3	0.831	15.2 ± 6.6	0.023 ^*
Reticulocyte count (× 10^9/L)^a	303.0 ± 97.3^c	331.3 ± 104.9	0.245	142.1 ± 122.6^d	0.007 ^*
Reticulocyte percentage (%)^b	15.7 (10.2–22.8)^c	19.9(13.6–31.3)	0.168	8.5 (4.2–17.1)^d	0.015 ^*
Hydrops, n (%)	15(19.0)	3 (13.6)	0.756	3 (33.3)	0.235
Number of IUTs^c	2(1–4)	3.5 (1–5)	0.167	5 (3–5)	0.007 ^*
Gestational age at birth^b, ^c	35.0 (33.9–36.6)	36.0 (33.4–36.9)	0.586	35.0(33.2–35.6)	0.331

ISSN: 1471-2393