| HDF (n = 120) | No HDF (n = 145) | P | Univariable OR (95% CI) | P | Multivariable ORb (95% CI) |
---|---|---|---|---|---|---|
Previous affected pregnancies per womana | 1(0–2) | 0 (0–0) | <0.001 | 5.66(3.561–9.006) | <0.001 | 5.34(3.156–9.036) |
Maternal transfusion history, n (%) | 18(15.0) | 21(14.5) | 0.906 | 0.96(0.485–1.898) | 0.021 | 3.74(1.219–11.464) |
Maternal antibody titrea | 1:512(1:256-1:1792) | 1:64(1:16 − 1:256)c | <0.001 | 1.00(1.001–1.002) | <0.001 | 1.00(1.001–1.002) |
Major ABO incompatibility, n (%) | 9(7.7)d | 26(19.8)e | 0.319 | 0.72(0.376–1.375) | 0.488 | 0.73(0.303–1.767) |
Types of maternal antibody | ||||||
 Anti-D, n (%) | 82(68.3) | 121(83.4) | - | - | - | - |
 Anti-D combined with others, n (%) | 23(19.1) | 15(10.3) | 0.024 | 2.26(1.114–4.594) | 0.598 | 0.74(0.246–2.246) |
 Other single-antibody, n (%) | 15(12.5) | 9(4.8) | 0.043 | 2.46(1.028–5.886) | 0.042 | 3.25(1.043–10.114) |