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Table 2 The incidence of severe HDF between different types of antibodies

From: Distribution of maternal red cell antibodies and the risk of severe alloimmune haemolytic disease of the foetus in a Chinese population: a cohort study on prenatal management

 

Anti-D

n = 203

Anti-D combined with others

n = 38

Other single-antibody

n = 24

Other multiple antibodies§

n = 03

HDF n(%)

82 (40.4)

23 (60.5)b

15 (62.5)b

2 (-)c

P

 

0.022

0.038

-

Severe HDFan(%)

73 (36.0)

21 (55.3)b

15 (62.5)b

2 (-)c

P

 

0.025

0.012

-

Severe anaemia n(%)

38 (18.7)

9 (23.7)

8 (33.3)

0

P

 

0.478

0.307

-

Hydrops fetalis n(%)

18 (8.9)

3 (7.9)

8 (33.3)b

0

P

 

> 0.999

0.002

-

Intrauterine demise n(%)

12 (5.9)

2 (5.3)

3 (12.5)

1 (-)c

P

 

> 0.999

0.202

-

IUT n(%)

64(31.5)

18 (47.4)

10 (41.6)

1 (-)c

P

 

0.059

0.316

-

Survival rate of HDF

 Foetuses

55 (67.1)

18 (78.3)

12 (80.0)b

1 (-)c

 P

 

0.303

0.380

-

 Neonates

55 (67.1)

18 (78.3)

9 (60.0)

1 (-)c

 P

 

0.303

0.595

-

  1. HDF haemolytic disease of the foetus; IUT intrauterine transfusion
  2. aFoetuses may fall into more than 1 severe HDF defining category
  3. bSignificant difference compared to the anti-D group
  4. cCan’t calculate the percentage because the denominator was less than 20
  5. §Can’t calculate the p value due to the small sample size in this group