Table 1 Summary of the demographic characteristics, reproductive history and the clinical outcomes of RIF patients and control patients
RIF patients (n = 155) | Good prognosis patients (n = 26) | P value | |
|---|---|---|---|
Age(y) | 33.0 ± 3.7 | 29.1 ± 2.8 | <0.001 |
Duration of infertility (year) | 5.6 ± 2.6 | 3.2 ± 1.9 | 0.022 |
BMI (kg/m2) | 20.9 ± 1.6 | 21.9 ± 2.3 | <0.001 |
Basal FSH level (mIU/ml) | 6.4 ± 2.7 | 5.6 ± 1.5 | 0.131 |
Endometrial thickness on the day of embryo transfer | 11.5 ± 1.5 | 11.1 ± 2.2 | 0.263 |
Cause of infertility | 0.367 | ||
Male factor | 20/155(12.9%) | 5/26 (19.3%) | |
Tubal factor | 135/155 (87.1%) | 21/26 (80.7%) | |
No. of previous failed cycles | 3.6 ± 0.7 | 1 | / |
The out of phase rate | 49/155 (31.6%) | 1/26 (3.8%) | 0.003 |
Total patients with 1st pFET/FET | 47 | 26 | |
High quality embryo rate | 33/47 (70.2%) | 20/26 (76.9%) | 0.793 |
Cleavage stage embryo | 3/47 (6.4%) | 3/26 (11.5%) | |
Blastocyst | 30/47 (63.8%) | 17/26 (65.4%) | |
Implantation rate after 1st pFET/FET | 32/67 (47.8%) | 23/41 (56.1%) | 0.400 |
Ongoing pregnancies rate after 1st pFET/FET | 29/47 (61.7%) | 21/26 (80.7%) | 0.093 |
Biochemical pregnancies after 1st pFET | 7/47 (14.9%) | 2/26 (7.6%) | 0.476 |
live birth rate after 1st pFET/FET | 27/47 (57.4%) | 21/26 (80.7%) | 0.07 |
Failed pregnancies after 1st pFET/FET | 11 | 3 | |
No. of 2nd biopsies at the specified day | 5 | / | |
2nd expectant endometrial dating | 5 | / | |
Total patients with 2nd pFET/FET | 5 | 2 | |
Implantation rate after 2nd pFET/FET | 3/7 (42.8%) | 0 | |
Ongoing pregnancies after 2nd pFET/FET | 3/5 (60%) | 0 | |
Accumulative live birth rate after pFET/FET | 29/47 (61.7%) | 21/26 (80.7%) | 0.093 |