Characteristic | aHUS | HELLP syndrome | Preeclampsia | TTP |
---|---|---|---|---|
Onset | Postpartum | Third trimester | Third trimester | Throughout pregnancy and postpartum |
MAHA | Frequently | Frequently | Seldom | Always |
Thrombocytopenia | Frequently | Frequently | Seldom | Always |
Hypertension | Uncommon | Seldom | Always | Uncommon |
DIC | Seldom | Always | Seldom | Uncommon |
Liver disease | Seldom | Always | Seldom | Seldom |
Renal disease | Always | Sometimes | Sometimes | Seldom |
CNS disease | Seldom | Seldom | Seldom | Always |
Management | Anticomplement therapy | Delivery and transfusion of blood products | Delivery | Plasmapheresis |